Focus On ToxPath 

Maronpot Consulting, LLC

Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP

Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, was selected by the Awards Committee as the 2008 Society of Toxicologic Pathology Achievement Award recipient. Dr. Maronpot has significantly influenced the field of toxicologic pathology in many different ways, including as a leader, manager, educator, and author. He is internationally recognized and highly respected for his scientific contributions to toxicologic pathology and the advancement of the Society of Toxicologic Pathology (STP). Dr. Maronpot served as president of STP in 2001 and as editor-in-chief of its journal, Toxicologic Pathology, from 2001 to 2004.
     Dr. Maronpot received his doctorate of veterinary medicine in 1965 from Michigan State University, an MS in nutritional pathology from Michigan State University in 1966, and an MPH from Harvard University in 1972. He is a diplomate of the American College of Veterinary Pathologists as well as the American Board of Toxicology and has worked more than forty years in experimental pathology, with an emphasis on animal models of carcinogenesis. He serves on several journal editorial boards. 

      In addition to more than 250 peer-reviewed publications, he has edited a comprehensive text titled Pathology of the Mouse (1999), coedited a book titled Pathology of Genetically Engineered Mice (2000), and has several years of experience in the application of imaging technologies, especially magnetic resonance imaging (MRI), to toxicologic pathology. In 2007, he retired from the National Institute of Environmental Health Sciences (NIEHS) and the National Toxicology Program (NTP), where he was chief of the Laboratory of Experimental Pathology.
     As a leader and manager, he started at the NIEHS as part of a very small, fledgling program of experimental pathology in 1981. During his appointment, his vision of increasing the impact of the pathologist in toxicology through a wider use of scientific tools was so successful that, by the end of his tenure, the program had expanded to fifty people, all dedicated to the elucidation of scientific issues in pathology. The pathologists on the current staff at NIEHS joined the program during his tenure and constitute a remarkable group of scientists.
     As an educator, Dr. Maronpot also created the training program at NIEHS, where many toxicologic pathologists have been trained through the years. The program maintains two to three trainees, therefore creating a scholarly learning environment. He was the originator of the NTP Symposium held in conjunction with the STP Symposium that has always been well received and considered an important component of the meeting. Dr. Maronpot also has adjunct faculty appointments at Duke University, North Carolina State University, and the University of North Carolina.
     In addition to his leadership role as editor of the Pathology of the Mouse, which is a seminal publication to all toxicologic pathologists, he was instrumental in organizing some of the first panels of pathologists to achieve better standardization of our terminology. Specifically impactful was his leadership in the definition of liver proliferative lesions as well as his role in the nomenclature of lesions of the forestomach. These early efforts set the tone for the achievement of consensus in the field and have been critical to the later achievement of clarity in our communication of risk assessment. Dr. Maronpot also contributed significantly to the use of in vivo imaging, particularly MRI and its use in the study of the development, progression, and regression of proliferative changes in rodents.
     Dr. Maronpot continues to advance the profession by working as a consultant and striving to address some of the issues of consistency between pathologists. He is frequently sought out to provide expert advice on numerous national and international committees, working groups, and task forces. He serves as an example to the present and future membership for his scientific achievements and selfless dedication to the profession.

CURRICULUM VITAE
March 2015


Robert R. Maronpot
Consultant in Toxicology and Pathology

Contact Information
Maronpot Consulting, LLC
Email: Maronpot@me.com

Education
B.S., 1963 (Veterinary Science), Michigan State University
D.V.M., 1965 (Veterinary Medicine), Michigan State University
M.S., 1966 (Nutritional Pathology), Michigan State University
M.P.H., 1972 (Public Health), Harvard University

Specialty Boards & Honors
Diplomate, American College of Veterinary Pathologists, 1973
Diplomate, American Board of Toxicology, 1980
Distinguished Postdoctoral Veterinary Alumnus Award from Michigan State University College of Veterinary Medicine - 2000
President, Society of Toxicologic Pathology - 2001-2002
Editor-in-Chief, Toxicologic Pathology  – 2001-2004
Board of Directors, American Board of Toxicology – 1989-1993
Society of Toxicologic Pathology Achievement Award - 2008
Fellow, International Academy of Toxicologic Pathology  – 2009
Vice President, International Academy of Toxicologic Pathology – 2010
President, International Academy of Toxicologic Pathology – 2011-Dec 2012
Secretary General, International Federation of Societies of Toxicologic Pathology – June 2014 - present

Recent Positions
Guest Researcher, Laboratory of Experimental Pathology: 2007-2008 National Institute of Environmental Health Sciences, NIH
Chief, Laboratory of Experimental Pathology: 1992 - 2007 National Institute of Environmental Health Sciences, NIH, National Toxicology Program

Professional Organizations
American College of Veterinary Pathologists
Society of Toxicologic Pathologists
Society of Toxicology
British Society of Toxicologic Pathology
European Society of Toxicologic Pathology


Lectures Since Retirement from NIEHS/National Toxicology Program
2007 Lectures
Society of Toxicology Annual Meeting Charlotte, NC – March 2007
Lectured at a Continuing Education Course Rodent Imaging Overview for the Toxicologist “Magnetic Resonance Imaging”

7th Biennial Industrial Toxicology & Pathology Short Course University of Illinois – July 2007
“Carcinogenicity Assessment” and “Application of Multimodality Imaging in Toxicologic Pathology”

American Association for Laboratory Animal Science Annual Meeting Charlotte, NC – October 2007
The Wallace P. Rowe Lecture
“The Cancer Bioassay: Challenges for the Future”
and Seminar on Current Imaging Modalities for Rodent Xenograft Models “MRI Imaging Systems”

National Academy of Science Workshop on Mouse Liver Tumors
Washington, DC – November 2007
“Mouse Models for Carcinogenicity”

American College of Veterinary Pathologists
Savannah, Georgia – November 2007
Lectured at a Continuing Education Course Rodent Imaging Overview for the Pathologist “Magnetic Resonance Imaging”

2008 - 2011 Lectures
ILSI Annual Meeting Rio Grande, Puerto Rico – January 2008
Organized symposium on “Applications of Small Animal Imaging in Toxicology Research and Testing”
Lectured on “Application of Magnetic Resonance Imaging in Toxicology and Toxicologic Pathology”

NIEHS February 2008 Lecture on “Comparative Medicine Branch Pathology/Case Presentations”

Aperio Research Triangle Park Digital Pathology Seminar May 13, 2008
Lecture on “Digital Pathology for Peer Review and Phenotyping”

NTP Satellite Symposium, STP Annual meeting. Conundrums in Toxicologic Pathology June 21, 2008, San Francisco

2nd East Mediterranean ICLAS Regional Meeting
“Overview of Imaging Modalities and Control of Small Animal Physiology During Live Imaging”
and “Application of MRI in Toxicology and Toxicologic Pathology”
Jerusalem, Israel, December 3-4, 2008.

TEVA Pharmaceutical Company, Israel “The Cancer Bioassay: Past, Present, Future” December 8, 2008

Eighth Biennial Short Course: Toxicology & Pathology Drug Discovery and Development.
University of Illinois, Champaign/Urbana, Illinois
“The Cancer Bioassay: Past, Present, and Future” - July 21, 2009

Contemporary Concepts in Target Organ Toxicologic Pathology: Hepatobiliary and Cardiovascular Systems
“Background Lesions and Nomenclature”
University of Illinois, Champaign/Urbana, Illinois 
“The Cancer Bioassay: Past, Present, and Future” - July 22, 2009

“Xenobiotic-induced Toxicologic Pathology of the Liver.”  The BSTP Gopinath Lecture. 
7th European Congress of Toxicologic Pathology, European Society of Toxicologic Pathology.  
The Hague September 15-18, 2009

“Xenobiotic-induced Rodent Tumors of Questionable Relevance to Human Cancer Risk” 
7th European Congress of Toxicologic Pathology, European Society of Toxicologic Pathology.  
The Hague September 15-18, 2009

“Histopathology of Non-neoplastic Liver Lesions”  
Osaka Perfecture University, Osaka, Japan  January 24, 2011.

“Rodent Lesions That Are Not Significant for Human Risk”  
Sumitomo Chemical Company (January 25, 2011), DaiichiSankyo (January 31, 2011) and IET (February 1, 2011).  Japan

“Adverse Versus Adaptive Hepatic Enzyme Induction (Hypertrophy)”
JSTP Annual Meeting, Osaka, Japan  January 27, 2011.

“Overview of Xenobiotic-Induced Hepatocellular Hypertrophy”  
3rd International European Society of Toxicologic Pathology Workshop, Ivrea, Italy.  June 1, 2011.

2012 Lectures
“Pathology of the Adrenal Gland” Daiichi-Sankyo, Tokyo, Japan January 31, 2012

“Rodent Pulmonary Lesions”  JSTP Annual Meeting, Tokyo, Japan February 1, 2012

“Current and Past Rat Strains Used by the National Toxicology Program”  Harlan Evening Seminar, Tokyo, Japan February 3, 2012

“Image Acquisition and Ethics”  IATP Lecture at STP Annual Meeting, Boston, MA , June 27, 2012

“Pathology of the Mouse: Past, Present and Future” ACVP Annual Meeting, Seattle, Oregon, December 4, 2012

“Mice in Toxicity Studies: Inbred vs. Outbred Strains and Challenges of Background Findings.  European Society of Toxicologic Pathology, Uppsala, Sweden, Sept. 10, 2011

2013 Lectures
“The Role of the Toxicologic Pathologist in the Post-Genomic Era”, 29th Annual Meeting of the Japanese Society of Toxicologic Pathology, Tsukba, Tokyo, Japan. January 31, 2013.

Responsible Authorship and Publication Practices, AALAS Annual Meeting, Baltimore, MD, 28 October 2013

2014 Lectures
Practical Applications of MRI Histology in Toxicologic Pathology
30th Annual Meeting of the Japanese Society of Toxicologic Pathology, Tokushima, Japan, January 29, 2014

Neoplastic and Non-neoplastic Rodent Thyroid Lesions and Their Relevance 
RTP Rodent Pathology Course, Research Triangle Park, NC, September 22, 2014

Identifying Adverse Organ Responses: The Liver as Paradigm
Annual Meeting of the American College of Toxicology, Orlando, Florida, November 11, 2014

2015 Lectures
Responsible Authorship & Publication Practices
31st Annual Meeting of the Japanese Society of Toxicologic Pathology, Tokyo, Japan, January 28, 2015

INHAND Master Class: Rodent Liver Lesions – Neoplastic, BSTP CE Symposium 3, Cambridge, UK; 25-27 March, 2015

Liver Lesions and Significance to Man, , BSTP CE Symposium 3, Cambridge, UK; 25-27 March, 2015

Liver Carcinogenesis and the Use of Rat and Mouse Models, , BSTP CE Symposium 3, Cambridge, UK; 25-27 March, 2015

Publications  
Maronpot  RR and Whitehair  CK, 1967. Experimental  Sprue-like  Small Intestinal  Lesions  in Pigs. Can. J. Comp. Med. 31:309-316.  

Maronpot  RR, Stedman  MA, and Bucci TJ, 1968. Focal Degenerative  Myopathy  in Turkeys.  Avian Dis. 12:96-103.

Stedham  MA, Bucci TJ, and Maronpot  RR, 1968. Sexual and Asexual  Phases  of Aspergillus Nidulans  in an Egret. Myopath.  et Mycologia  Appli. 36:289-292.  

Maronpot  RR and Michael  SA, 1968. Toxoplasmosis  in Sheep. A Review.  J. Egypt. Vet. Med. Assoc. 28:155-163.  

Maronpot  RR and Guindy E, 1970. Preliminary  Study of Babesia  Gibsoni  Patton in Wild Carnivores and Domesticated  Dogs in Egypt. Amer. J. Vet. Res. 31:797-799.  

Maronpot  RR and Ezzat E, 1970. Hematologic  Values for Cairo Dogs. Proc. 9th Arab Vet. Congress,  Cairo, Egypt. pp. 124-134.

Maronpot  RR and Abd El Hei Refaii, 1970. The Histopathology  of Klosiella  Equi in Egyptian Equines.  Proc. 9th Arab Vet. Congress,  Cairo, Egypt. pp. 226-235.  

Botros BA M, Awad AY, Kozman  AR, Hildebrandt  PK, and Maronpot  RR, 1970. Hematologic,  Blood Electrolyte  and Blood Biochemical  Values of Egyptian  Domesticated  Animals.  J. Egypt. Vet. Med Assoc. 30: 53-61  

Michael  SA, Maronpot  RR, and Botros BAM, 1970. Blood Parasites  in Egyptian  Animals.  Proc. 9th Arab Vet. Congress,  Cairo, Egypt. pp. 236-254.

Waslien  CI, Maronpot  RR, and Kozman  AR, 1970. Nutritional  Studies  in the Sand Rat (Psammomys  obesus).  Pahlavi  Medical  J. 1:228-233.  

Maronpot  RR, Barsoum  IS, and Ezzat E, 1971. Canine  Leptospirosis  in Cairo. United Arab Republic.  The J. of Infectious  Diseases.  123:548-550.

Wilson BJ and Maronpot  RR, 1971. Causative  Fungus  Agent of Leukoencephalomalacia  in Equine Animals.  Vet. Rec. 88:484-486.  

Attia MAM, Williams  RE, Maronpot  RR, El Mour AF, and Moussa  MI, 1971. Pathogenicity  of Wad Medani  Virus to Selected  Animals.  J. Egypt. Pub. Hlth. Assoc. 46:326-336.  

Maronpot  RR, 1972. Erythrocyte  Glucose-6-phosphate  Dehydrogenase  and Glutathione  Deficiency in Sheep. Can. J. Comp. Med. 36:55-60.

Maronpot  RR and Barsoum  IS, 1972. Leptospiral  Microscopic  Agglutinating  Antibodies  in Sera of Man and Domestic  Animals  in Egypt. Amer. J. Trop. Med. Hyg. 21:467-472.  

Maronpot  RR and Botros BAM, 1972. Toxoplasma  Serologic  Survey  in Man and Domestic  Animals in Egypt. J. Egypt. Pub. Hlth. Assoc. 47:58-67.  

Wilson BJ, Maronpot  RR, and Hildebrandt  PK, 1973. Equine  Leukoencephalomalacia.  J. Amer. Vet. Med. Assoc. 163:1293-1295.  

Maronpot  RR, Michael  SA, and Botros BAM, 1974. Blood Parasites  in Egyptian  Domestic  Animals. J. Egypt. Vet. Med. Assoc. 34:301-308.  

Botros BAM and Maronpot  RR, 1974. Complement-fixing  and Indirect  Fluorescent  Antibodies  in Sera of Dogs Experimentally  Infected  with Babesia  Gibsoni.  J. Egypt. Vet. Med. Assoc. 34:309-321.

Hoffman  D, Raineri R, Hecht S, Maronpot  RR, and Wynder  EL, 1975. A Study of Tobacco Carcinogenesis.  XIV. Effects of N'-nitrosonornicotine  and N'-nitrosoanabasine  in Rats. JNCI 55:977-981.  

Hecht SS, Thorne  RL, Maronpot  RR, and Hoffman  D, 1975. A Study of Tobacco  Carcinogenesis. XIII. Tumor Promoting  Subfractions  of the Weakly  Acidic Fraction.  JNCI 55:1329-1336.  

Hecht SS, Loy M, Maronpot  RR, and Hoffmann  D, 1976. A Study of Chemical  Carcinogenesis: Comparative  Carcinogenicity   of 5-Methylchrysene,   Benzo  (a) Pyrene  and Modified  Chrysenes. Cancer Ltrs. 1:147-153.  

Narisawa  T, Wong CQ, Maronpot  RR, and Weisburger  JH, 1976. Large Bowel Carcinogenesis  in Mice and Rats by Several  Intrarectal  doses of Methylnitrosourea   and Negative  Effect of Nitrite plus Methylurea.  Cancer Res. 36:505-510.  

Maronpot  RR and Chavannes  JM, 1977. Dacryoadenitis,  Conjunctivitis,  and Facial Dermatitis  of the Mouse.  Lab. Anim. Sci. 27:277.  

Anderson  LM, Budinger  JM, Maronpot  RR, and Good RA, 1978. Transplacental  Lung Tumorigenesis  in the Athymic  Mouse.  Cancer Res. 38:137-141.  

McGee  MA and Maronpot  RR, 1979. Harderian  Gland Dacryoadenitis  in Rats Resulting  from Orbital Bleeding.  Lab. Anim. Sci. 29:639-641.  

Burton DS, Maronpot  RR, and Howard  FL, 1979. Frequency  of Hydronephrosis  in Wistar Rats. Lab. Anim. Sci. 29:642-644.  

Maronpot  RR and Peterson  LG, 1981. Spontaneous  Proteus  Nephritis  Among  Male C3H/HeJ  Mice. Lab. Anim. Sci. 31:697-700.  

Snellings  WM, Maronpot  RR, Zelenak  JP, and Laffoon  CP, 1982. Teratology  Study in Fischer  344 Rats Exposed  to Ethylene  Oxide by Inhalation.  Tox. & Appl. Pharmacol.  64:476-481.  

Maronpot  RR and Boorman  GA, 1982. Interpretation  of Rodent Hepatocellular  Proliferative Alterations  and Hepatocellular  Tumors  in Chemical  Safety Assessment.  Tox. Path. 10:71-80.    

Maronpot  RR, Witschi  HP, Smith LH, and McCoy  JL, 1983. Recent  Experience  with the Strain A Mouse Pulmonary  Tumor Bioassay Model. In Short-Term  Bioassays in the Analysis of Complex Environmental  Mixtures  III. Environ.  Sci. Res. 27:341-350.    

Dodd DE, Snellings  WM, Maronpot  RR, and Ballantyne  B, 1983. Ethylene  Glycol Monobutyl  Ether: Acute, 9-day, and 90-day Vapor Inhalation  Studies  in Fischer  344 Rats. Tox. & Appl. Pharmacol. 68:405-414.  

Maronpot  RR, Zelenak  JP, Weaver  EV, and Smith NJ, 1983. Teratogenicity  Study of Ethylene Glycol in Rats. Drug & Chem. Toxicol.  6:579-594.  

Yang RSH, Garman  RH, Maronpot  RR, McKelvey  JA, Weil CS, and Woodside  MD, 1983. Acute and Subchronic  Toxicity  of Ethylenediamine   in Laboratory  Animals.  Fund. & Appl. Tox. 3:512-520.  

Snellings  WM, Weil CS, and Maronpot  RR, 1984. A Two-Year  Inhalation  Study of the Carcinogenic Potential  of Ethylene  Oxide in Fischer  344 Rats. Tox. & Appl. Pharmacol.  75:105-117.  

Kluwe  WM, Maronpot  RR, Greenwell  A, Harrington  F, 1984.  Interactions  Between  Bromobenzene Dose, Glutathione  Concentrations,   and Organ  Toxicities  in Single  and Multiple  Treatment  Studies. Fund. & Appl. Tox. 4:1019-1028.  

Snellings  WM, Weil CS, and Maronpot  RR, 1984. A Subchronic  Inhalation  Study on the Toxicologic Potential  of Ethylene  Oxide in B6C3F1  Mice. Tox. & Appl. Pharmacol.  76:510-518.  

Agarwal  DK, Maronpot  RR, Lamb IV JC, and Kluwe WM, 1985. Adverse  Effects of Butyl Benzyl Phthalate  on the Reproductive  and Hematopoietic  System  of Male Rats. Toxicology  35:189-206.

Choy WN, MacGregor  JT, Shelby MD, and Maronpot  RR, 1985. Induction  of Micronuclei  by Benzene  in B6C3F1  Mice: Retrospective  Analysis  of Peripheral  Blood Smears  from the NTP Carcinogenesis  Bioassay.  Mutation  Res. 143:55-59.  

Ghanayem  BI, Maronpot  RR, and Matthews  HB, 1985. Ethyl Acrylate-Induced   Gastric Toxicity.  I. Effect of Single and Repetitive  Dosing.  Tox. & Appl. Pharmacol.  80:323-335.  

Ghanayem  BI, Maronpot  RR, and Matthews  HB, 1985. Ethyl Acrylate-Induced   Gastric Toxicity.  II. Structure  - Toxicity  Relationships  and Mechanism.  Tox. & Appl. Pharmacol.  80:336-  344.  

Garman  RH, Snellings  WM, and Maronpot  RR, 1985. Brain Tumors  in F344 Rats Associated  with Chronic  Inhalation  Exposure  to Ethylene  Oxide . NeuroToxicology   6:117-138.  

Lamb JC, Maronpot  RR, Gulati DK, Russell  VS, Hommel  L, and Sabharwal  PS, 1985. Reproductive and Developmental  Toxicity  of Ethylene  Glycol in the Mouse.  Tox. & Appl. Pharmacol.  81:100-112.  

Dieter MP, Maronpot  RR, and French  JF, 1985. Comparison  of the Morphology  and Enzyme Activity of Mononuclear  Cells From Fischer  344 Rats with Either Spontaneous  or Transplanted Leukemia.  Cancer Res. 45:4301-4307.  

Cline JM and Maronpot  RR, 1985. Variations  in the Histologic  Distribution  of Rat Bone Marrow Cells with Respect  to Age and Anatomic  Site. Tox. Path. 13:349-355.  

DePass  LR, Maronpot  RR, and Weil WS, 1985. Dermal Oncogenicity  Bioassays  of Monofunctional and Multifunctional  Acrylates  and Acrylate-based  Oligomers.  J. Tox. and Environ.  Hlth. 16:55-60.  

DePass  LR, Garman  RH, Woodside  MD, Boyce JT, Giddens  WE, Maronpot  RR, and Weil CS, 1986. Chronic  Toxicity  and Oncogenicity  Studies  of Ethylene  Glycol in Rats and Mice. Fund. &. Appl. Tox. 7:547-565.  

DePass  LR, Woodside  MD, Maronpot  RR, and Weil CS, 1986. Three-Generation   Reproduction  and Dominant  Lethal Mutagenesis  Studies  of Ethylene  Glycol in the Rat. Fund. & Appl. Tox. 7:566- 572.    

Garman  RH, Snellings  WM, and Maronpot  RR, 1986. Frequency,  Size and Location  of Brain Tumours  in F-344 Rats Chronically  Exposed  to Ethylene  Oxide. Fd. Chem. Tox. 24(2):145-153.  

Reynolds  SH, Stowers  SJ, Maronpot  RR, Anderson  MW, and Aaronson  SA, 1986. Detection  and Identification  of Activated  Oncogenes  in Spontaneously  Occurring  Benign  and Malignant Hepatocellular  Tumors  of the B6C3F1  Mouse.  Proc. Nat'l. Acad. Sci. 83:33-37.  

Klinger W, Devereux  T, Maronpot  RR, and Fouts J, 1986. Functional  Hepatocellular  Heterogeneity Determined  by the Hepatotoxins  Allyl Alcohol  and Bromobenzene  in Immature  and Adult F344 Rats. Tox. & Appl. Pharmacol.  83:108-114.  

Maronpot  RR, Montgomery  CA, Boorman  GA, and McConnell  EE, 1986. National  Toxicology Program  Nomenclature  for Hepatoproliferative   Lesions  of Rats. Tox. Path. 14:163-273.  

Maronpot  RR, Shimkin  MB, Smith LH, Witschi HP, and Cline JM, 1986. Strain A Mouse Pulmonary Tumor Test Results  for Chemicals  Previously  Tested in the National  Cancer Institute Carcinogenicity  Tests. JNCI. 76:1101-1112.  

Maronpot  RR, Miller RA, Clarke WJ, Westerberg  RB, Decker JR, and Moss OR, 1986. Toxicity  of Formaldehyde  Vapor in B6C3F1  Mice Exposed  For 13 Weeks.  Toxicology  41:253-266.  

Ghanayem  BI, Maronpot  RR, and Matthews  HB, 1986. Association  of Chemically  Induced Forestomach  Cell Proliferation  and Carcinogenesis.   Cancer Ltrs. 32:271-278.  

Ghanayem  BI, Maronpot  RR, and Matthews  HB, 1986. Ethyl Acrylate-Induced   Gastric Toxicity.  III. Development  and Recovery  of Lesions.  Tox. & Appl. Pharmacol.  83:576-583.  

Boorman  GA, Hong HL, Jameson  CW, Yoshitomi  K, and Maronpot  RR, 1986. Regression  of Methyl Bromide  Induced  Forestomach  Lesions  in the Rat. Tox. & Appl. Pharmacol.  86:131-139

Yoshitomi  K, Maronpot  RR, Solleveld  HA, and Boorman  GA, 1986. Forestomach  Ulcers in Crj:B6C3 (C57BL/6NCrj  x C3H/HeNCrj)  F1 Mice. Lab. Anim. Sci. 36(5):501-503.  

Wilson WE, Hudson  PM, Kanamatsu  T, Walsh TJ, Tilson HA, Hong JS, Maronpot  RR, and Thompson  M, 1986. Trimethyltin-  Induced  Alterations  in Brain Amino Acids, Amines  and Amine Metabolites:  Relationship  to Hyperammonemia.  NeuroToxicology   7(3):63-74.  

Dieter MP, Maronpot  RR, and French  JE, 1987. Biochemical  Markers  for Fischer  Rat Leukemia  in a Cell Transplant  Model. Cancer Detection  and Prevention  10:425-433.  

Ghanayem  BI, Matthews  HB, and Maronpot  RR, 1987. Calcium  Channel  Blockers  Protect Against Ethanol  - and Indomethacin-  Induced  Gastric Lesions  in Rats. Gastroenterology   92:106-111.  

Miller BE, Chapin  RE, Pinkerton  KE, Gilmore  LB, Maronpot  RR, and Hook GER, 1987. Quantitation of Silica-Induced  Type II Cell Hyperplasia  by Using Alkaline  Phosphatase  Histochemistry  in Glycol Methacrylate  Embedded  Lung. Exp. Lung Res. 12:135-148.  

Maronpot  RR, Haseman  JK, Boorman  GA, Eustis SE, Rao GN, and Huff JE, 1987. Liver Lesions  in B6C3F1  Mice: The National  Toxicology  Program,  Experience  and Position.  Arch. Toxicol.  Suppl. 10:10-26.  

Mitsumori  K, Maronpot  RR, and Boorman  GA, 1987. Spontaneous  Tumors  of the Meninges  in Rats. Vet. Path. 24:50-58.  

Melnick  RL, Jameson  CW, Goehl TJ, Maronpot  RR, Collins BJ, Greenwell  A, Harrington  FW, Wilson RE, Tomaszewski  KE, and Agarwal  DK, 1987. Application  of Microencapsulation  for Toxicology  Studies.  II. Toxicity  of Microencapsulated   Trichloroethylene   in Fischer  344 Rats. Fund. & App. Tox. 8:432-442.  

Maronpot  RR, 1987. Ovarian  Toxicity  and Carcinogenicity  in Eight Recent National  Toxicology Program  Studies.  EHP 73:125-130.  

Campen  DB, Sloop TC, Maronpot  RR, and Lucier GW, 1987. Continued  Development  of Hepatic  g- Glutamyltranspeptidase  - Positive  Foci Upon Withdrawal  of 17-a-Ethynylestradiol  in Diethylnitrosamine-initiated Rats. Cancer Res. 47:2328-2333.  

Stowers  SJ, Glover PL, Reynolds  SH, Boone LR, Maronpot  RR, and Anderson  MW, 1987. Activation  of the K-ras Protooncogene  in Lung Tumors  from Rats and Mice Chronically  Exposed  to Tetranitromethane.  Cancer Res. 47:3212-3219.  

Hsieh LL, Hsiao WL, Peraino  C, Maronpot  RR, and Weinstein  IB, 1987. Expression  of Retroviral Sequences  and Oncogenes  in Rat Liver Tumors  Induced  by Diethylnitrosamine.  Cancer Res. 47:3421-3424.  

Belinsky  SA, Walker VE, Maronpot  RR, Swenberg  JA, and Anderson  MW, 1987. Molecular Dosimetry  of DNA Adduct Formation  and Cell Toxicity  in Rat Nasal Mucosa  Following  Exposure  to the Tobacco  Specific  Nitrosamine  (N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone  and their Relationship  to Induction  of Neoplasia.  Cancer Res. 47:6058-6065.  

Mitsumori  K, Dittrich  KL, Stefanski  S, Talley FA, and Maronpot  RR, 1987. Immunohistochemical and Electron  Microscopic  Study of Meningeal  Granular  Cell Tumors  in Rats. Vet. Path. 24:356-359.  

Ghanayem  BI, Blair P, Thompson  MB, Maronpot  RR, and Matthews  HB, 1987. Effect of Age on the Toxicity  and Metabolism  of Ethylene  Glycol Monobutyl  Ether (2-Butoxyethanol)   in Rats. Tox. & Appl. Pharmacol.  91:222-234.  

Reynolds  SH, Stowers  SJ, Patterson  RM, Maronpot  RR, Aaronson  SA, and Anderson  MW, 1987. Activated  Oncogenes  in B6C3F1  Mouse Liver Tumors:  Implications  For Risk Assessment.  Science 237:1309-1316.

Stowers  SJ, Maronpot  RR, Reynolds  SH, and Anderson  MW, 1987. The Role of Oncogenes  in Chemical  Carcinogenesis.  EHP 75:81-86.  

Pitot HC, Goldsworthy  T, Moran  S, Kennan  W, Glauert  H, Maronpot  RR, and Campbell  HA, 1987. A Method  to Quantitate  the Relative  Initiating  and Promoting  Potencies  of Hepatocarcinogenic  Agents in Their Dose-Response   Relationships  to Altered  Hepatic  Foci. Carcinogenesis  8:1491-1499.  

Goering  PL, Maronpot  RR, and Fowler BA, 1988. Effect of Intratracheal  Gallium  Arsenide Administration  on d-Aminolevulinic   Acid Dehydratase  in Rats: Relationship  to Urinary  Excretion  of Aminolevulinic  Acid. Toxicol.  Appl. Pharmacol.  92:179-193.  

Reynolds  SH, Stowers,  SJ, Patterson  RM, Maronpot  RR, and Anderson  MW, 1988. Oncogene Activation  in Spontaneous  and Chemically  Induced  Rodent Tumors:  Implications  for Risk Analysis. EHP 78:175-177.  

Hong HL, Huff JE, Luster MI, Maronpot  RR, Dieter MP, Hayes  HT, and Boorman  GA, 1988. The Effects  of Allyl Isovalerate  on the Hematopoietic  and Immunologic  Systems  in Rodents.  Fund. & Appl. Tox. 10:655-663.  

Belinsky  SA, Dolan ME, White CM, Maronpot  RR, Pegg AE, and Anderson  MW, 1988. Cell Specific Differences  in O6-Methylguanine-  DNA Methyltransferase   Activity  and Removal  of 06- Methylguanine in Rat Pulmonary  Cells. Carcinogenesis  9:2053-2058.  

Peraino  C, Carnes BA, Stevens  FJ, Staffeldt  EF, Russell JR, Prapuolenis  A, Blomquist  JA, Vesselinovitch  SD, and Maronpot  RR, 1988. Comparative  Developmental  and Phenotypic Properties  of Altered  Hepatocyte  Foci and Hepatic  Tumors  in Rats. Cancer Res. 48:4171-4178  

Germolec  DR, Maronpot  RR, Ackermann  MF, Vore SJ, Dittrich  K, Rosenthal  GJ, and Luster MI, 1988. Lack of a Relationship  Between  Immune  Function  and Chemically  Induced Hepatocarcinogenesis  in B6C3F1  Mice. Cancer Immunology  Immunotherapy   27:121-127.  

Maronpot  RR, Ulland B, and Mennear  J, 1988. Transplantation  Characteristics,  Morphologic Features,  and Interpretation  of Preputial  Gland Neoplasia  in the Fischer-344  Rat. EHP 77:33-36  

Dixon D, Johnson  GA, Cofer GP, Hedlund  L.W, and Maronpot  RR, 1988. Magnetic  Resonance Imaging  (MRI): A New Tool in Experimental  Toxicologic  Pathology.  Tox. Path. 16:386-391.  

Graham  MJ, Lucier GW, Linko P, Maronpot  RR, Goldstein  JA, 1988. Increases  in Cytochrome  P- 450 Mediated  17-b-Estradiol  2- Hydroxylase  Activity  in Rat Liver Microsomes  after both Acute Administration  and Subchronic  Administration  of 2,3,7,8-Tetrachlorodibenzo- p-dioxin  in a Two- stage Hepatocarcinogenesis  Model. Carcinogenesis  9:1935-  1941.  

Goldstein  JA, Graham  MJ, Sloop T, Maronpot  RR, Goodrow  T, and Lucier GW, 1989. Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin  (TCDD)  on Estradiol  Metabolism,  Enzyme-altered  Foci in a Two stage Hepatocarcinogenesis  Model in Rats. Chemosphere  18:695-700.  

Pitot HC, Goodspeed  D, Dunn T, Hendrich  S, Maronpot  RR, and Moran S, 1989. Regulation  of the Expression  of Some Genes for Enzymes  of Glutathione  Metabolism  in Hepatotoxicity  and Hepatocarcinogenesis.  Tox. & Appl. Pharmacol.  97:23-34.  

You M, Candrian  U, Maronpot  RR, Stoner GD, and Anderson  MW, 1989. Activation  of the Ki-ras Protooncogene  in Spontaneously  Occurring  and Chemically  Induced  Lung Tumors  of the Strain A Mouse.  Proc. Natl. Acad. Sci. 86:3070-3074.  

Johnson  GA, Thompson  MB, Cofer GP, Campen  D, and Maronpot  RR, 1989. Magnetic  Resonance Imaging  of Hepatic  Neoplasms  in the Rat. Vet. Path. 26:303-308.

Farmer THR, Johnson  GA, Cofer GP, Maronpot  RR, Dixon D, and Hedlund  LW, 1989. Implanted Coil MR Microscopy  of Renal Pathology.  Magnetic  Resonance  in Medicine.  10:310-323.  

Huff JE, Haseman  JK, Demarini  DM, Eustis S, Maronpot  RR, Peters AC, Persing  RL, Chrisp CE, and Jacobs AC, 1989. Multiple-Site  Carcinogenicity  of Benzene  in Fischer-344  Rats and B6C3F1 Mice. EHP 82:125-163.  

Belinsky  SA, Devereux  TR, Maronpot  RR, Stoner GD, and Anderson  MW, 1989. Relationship between  the Formation  of Promutagenic  Adducts  and the Activation  of the K-ras Protooncogene  in Lung Tumors  from A/J Mice Treated  with Nitrosamines.  Cancer Res. 49:5305-5311.  

Ulland BM, Maronpot  RR, Lemen JK, and Mennear  JH, 1989. Transplantation  Studies  of Preputial Gland and Epithelial  Skin Neoplasms  Derived  from Benzidine-based   Dye Carcinogenicity  Assays in Fischer  344 Male Rats. Tox. Path. 17:50-56.  

Harada  T, Maronpot  RR, Morris RW, Stitzel KA, and Boorman  GA, 1989. Morphological  and Stereological  Characterization   of Hepatic  Foci of Cellular  Alteration  in Control Fischer  344 Rats. Tox. Path. 17:579-593.  

Pitot, HC, Campbell,  HA, Maronpot  R, Bawa N, Rizva TA, Xu Y, Sargent  L, Dragan  Y, and Pyron M, 1989. Critical Parameters  in the Quantitation  of the Stages of Initiation,  Promotion,  and Progression in One Model of Hepatocarcinogenesis  in the Rat. Tox. Path. 17:594-612.  

Johnson,  GA and Maronpot  RR, 1989. Magnetic  Resonance  Microscopy  of Chemically-induced Liver Foci. Tox. Path. 17:613-616.  

Maronpot  RR, Pitot HC, and Peraino  C, 1989. Use of Rat Liver Altered  Focus Models for Testing Chemicals  that have Completed  Two-year  Carcinogenicity  Studies.  Tox. Path. 17:651-662.  

Maronpot  RR, Harada  T, Murthy ASK, and Boorman  GA, 1989. Documenting  Foci of Hepatocellular Alteration  in Two-year  Carcinogenicity  Studies:  Current  Practices  of the National  Toxicology Program.  Tox. Path. 17:675-684.  

Harada  T, Maronpot  RR, Morris RW, and Boorman  GA, 1989. Observations  on Altered Hepatocellular  Foci in National  Toxicology  Program  Two-year  Carcinogenicity  Studies  in Rats. Tox. Path. 17:690-708.  

Reynolds  SH, Patterson  RM, Mennear  JH, Maronpot  RR, and Anderson  MW, 1990. Ras Gene Activation  in Rat Tumors  Induced  by Benzidine  Congeners  and Derived  Dyes. Cancer Res. 50:266- 272.  

Campen  D, Maronpot  RR, and Lucier G, 1990. Dose-response  Relationships  in Promotion  of Rat Hepatocarcinogenesis  by 17-a-ethinylestradiol.  J. Tox. & Environ.  Hlth. 29:257-268.  

Harada  T, Maronpot  RR, Morris RW, and Boorman  GA, 1990. Effects of Mononuclear  Cell Leukemia  on Altered  Hepatocellular  Foci in Fischer  344 Rats. Vet. Path. 27:110-116.  

Xu YH, Campbell  HA, Sattler GL, Hendrich  S, Maronpot  R, Sato K, and Pitot HC, 1990. Quantitative  Stereological  Analysis  of the Effects of Age and Sex on Multistage Hepatocarcinogenesis  in the Rat by Use of 4 Cytochemical  Markers.  Cancer Res. 50:472-479.  

Xu YH, Maronpot  RR, and Pitot HC, 1990. Quantitative  Stereologic  Study of the Effects of Varying the Time Between  Initiation  and Promotion  on 4 Histochemical  Markers  in Rat-liver  During Hepatocarcinogenesis.  Carcinogenesis  11:267-272.  

Dieter MP, Jameson  CW, Maronpot  RR, Langenbach  R, and Braun AG, 1990. The Chemotherapeutic   Potential  of Glycol Alkyl Ethers: Structure-  activity Studies  of Nine Compounds in a Fischer  Rat Leukemia  Transplant  Model. Cancer Chemo.  & Pharmacol.  26: 173-180.

Uraih LC and Maronpot  RR, 1990. Normal Histology  of the Nasal Cavity and Application  of Special Techniques.  EHP 85: 187-208.  

Maronpot  RR, 1990. Pathology  Working  Group Review  of Selected  Upper Respiratory  Tract Lesions  in Rats and Mice. EHP 85: 331-352.  

Belinsky  SA, Foley JF, White KM, Anderson  MW, and Maronpot  RR, 1990. Dose-response Relationship  Between  O6-methylguanine   Formation  in Clara Cells and Induction  of Pulmonary Neoplasia  in the Rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.  Cancer Res. 50: 3772- 3780.  

Goodrow  T, Reynolds  S, Maronpot  R, and Anderson  M, 1990. Activation  of K-ras by Codon 13 Mutations  in C57BL/6  x C3H F1 Mouse Tumors  Induced  by Exposure  to 1,3-butadiene.  Cancer Res. 50: 4818-4823.  

Dittrich KL, Smith R, and Maronpot  RR, 1990. Stability  of Gamma-glutamyltranspeptidase  (GGT) in Paraffin  Embedded  Liver Tissue. The J. of Histotechnology   13:185-187.  

Cunningham  ML, Foley J, Maronpot  RR, and Matthews  HB, 1991. Correlation  of Hepatocellular Proliferation  with Hepatocarcinogenicity  Induced  by the Mutagenic  Noncarcinogen:Carcinogen pair - 2,6- and 2,4-diaminotoluene.  Tox. & Appl. Pharmacol.  107:562-567.  

Lucier GW, Trischer  A, Goldsworthy  T, Foley J, Clark G, Goldstein  J, and Maronpot  RR, 1991. Ovarian  Hormones  Enhance  2, 3, 7, 8- tetrachlorodibenzo-p-dioxin-mediated  Increases  in Cell Proliferation  and Preneoplastic  Foci in a Two-stage  Model for Rat Hepatocarcinogenesis.  Cancer Res. 51:1391-1397.  

Dragan  YP, Rizvi T, Xu YH, Hully JR, Bawa N, Campbell  HA, Maronpot  RR, and Pitot HC, 1991. An Initiation-Promotion  Assay in Rat Liver as a Potential  Complement  to the 2-year Carcinogenesis Bioassay.  Fund. & Appl. Tox. 16:525-547.  

Dixon D, Horton J, Haseman  JK, Talley F, Greenwell  A, Nettesheim  P, Hook GE, and Maronpot RR, 1991. Histomorphology   and Ultrastructure  of Spontaneous  Pulmonary  Neoplasms  in Strain A Mice. Exp. Lung Res. 17:131-155.  

Foley JF, Anderson  MW, Stoner GD, Gaul BW, Hardisty  JF, and Maronpot  RR, 1991. Proliferative lesions  of the Mouse Lung: Progression  Studies  in Strain A Mice. Exp. Lung Res. 17:157-168.  

Belinsky  SA, Devereux  TR, White CM, Foley JF, Maronpot  RR, and Anderson  MW, 1991. Role of Clara Cells and Type II cells in the Development  of Pulmonary  Tumors  in Rats and Mice Following Exposure  to a Tobacco-specific   Nitrosamine.  Exp. Lung Res. 17:263-278.  

Maronpot  RR, Palmiter  RD, Brinster  RL, and Sandgren  EP, 1991. Pulmonary  Carcinogenesis  in Transgenic  Mice. Exp. Lung Res. 17:305-320.  

You M, Wang Y, Lineen A, Stoner GD, You L, Maronpot  RR, and Anderson  MW, 1991. Activation  of Protooncogenes   in Mouse Lung Tumors.  Exp. Lung Res. 17:389-400.  

Maronpot  RR, 1991. Correlation  of Data from the Strain A Mouse Bioassay  with Long-term Bioassays.  Exp. Lung Res. 17:425-431.  

Ghanayem  BI, Maronpot  RR, and Matthews  HB, 1991. Effects of Sulfhydryl  Modulation  on Ethyl Acrylate-induced   Forestomach  Toxicity.  Tox. Ltrs. 55:215-221.  

Blair PC, Thompson  MB, Wilson RE, Esber HH, and Maronpot  RR, 1991. Correlation  of Changes  in Serum  Analytes  and Hepatic  Histopathology  in Rats Exposed  to Carbon  Tetrachloride.  Tox. Ltrs. 55:149-159.  

Hedlund  LW, Maronpot  RR, Johnson  GA, Cofer GP, Mille GM, and Wheeler  CT, 1991. Magnetic Resonance  Microscopy  of Toxic Renal Injury Induced  by Bromoethylamine   in Rats. Fund. & Appl. Tox. 16:787-797.

Candrian  U, You M, Goodrow  T, Maronpot  RR, Reynolds  SH, and Anderson  MW, 1991. Activation of Protooncogenes   in Spontaneously  Occurring  non-Liver  Tumors  from C57BL/6  x C3H F1 Mice. Cancer Res. 51:1148-1153.  

Greenwell  A, Foley J.F, and Maronpot  RR, 1991. An Enhancement  Method  for Immunohistochemical  Staining  of Proliferating  Cell Nuclear  Antigen  in Archival  Rodent  Tissues. Cancer Ltrs. 59:251-256.  

Dixon D, Marshall  KLE, Greenwell  A, Shimizu  T, Nettesheim  P, and Maronpot  RR, 1991. Comparison  of Automated  and Manual  Staining  Techniques  for the Binding  of Wheat Germ Agglutinin  (WGA) in Modified  B5- and Formalin-fixed  Pulmonary  Tissue. The J. of Histotechnology 14:149-153.  

Maronpot  RR, Giles HD, Dykes DJ, and Irwin RD, 1991. Furan-induced  Hepatic Cholangiocarcinomas  in Fischer  344 Rats. Tox. Path. 19:561-570.   Brown HR, Monticello  TM, Maronpot  RR, Randall  HW, Hotchkiss  JR, and Morgan  KT, 1991. Proliferative  and Neoplastic  Lesions  in the Rodent Nasal Cavity. Tox. Path. 19:358-372.  

Dixon D and Maronpot  RR, 1991. Histomorphologic   Features  of Spontaneous  and Chemically- induced  Pulmonary  Neoplasms  in B6C3F1  Mice and Fischer  344 Rats. Tox. Path. 19:540-556.  

Foley JF, Dietrich  DR, Swenberg  JA, and Maronpot  RR, 1991. Detection  and Evaluation  of Proliferating  Cell Nuclear  Antigen  (PCNA)  in Rat Tissue by an Improved  Immunohistochemical Procedure.  The J. of Histotechnology   14:237-241.  

Ghanayem  BI, Matthews  HB, and Maronpot  RR, 1991. Sustainability  of Forestomach  Hyperplasia in Rats Treated  with Ethyl Acrylate  for 13 Weeks  and Regression  After Cessation  of Dosing.  Tox. Path. 19:273-279.  

Whitehead  Jr. RE, Sugawara  O, Maronpot  RR, Gladen  BC, and Barrett JC, 1992. Detection  of Multiple  Tumor Suppressor  Genes for Syrian Hamster  Fibrosarcomas  by Somatic  Cell Hybridization.  Somatic  Cell and Molecular  Genetics  18:131-142.  

Belinsky  SA, Devereux  TR, Foley JF, Maronpot  RR, and Anderson  MW, 1992. Role of the Alveolar type-II Cell in the Development  and Progression  of Pulmonary  Tumors  Induced  by 4- (methylnitrosamino)-1-  (3-pyridyl)-1-butanone  in the A/J Mouse.  Cancer Res. 52:3164-3173.  

Lindamood  III C, Farnell DR, Giles HD, Prejean  JD, Collins JJ, Takahashi  K, and Maronpot  RR, 1992. Subchronic  Toxicity  Studies  of t-butyl Alcohol  in Rats and Mice. Fund. & Appl. Tox. 19:91- 100.  

You M, Wang Y, Stoner G, You L, Maronpot  R, Reynolds  S, and Anderson  M, 1992. Parental  Bias of Ki-ras Oncogenes  Detected  in Lung Tumors  from Mouse Hybrids.  Proc. Natl. Acad. Sci, USA 89:5804-5808.  

Dieter MP, Maronpot  RR, Jameson  CW, and Ward SM, 1992. The Effects of Iodinated  Glycerol, Trichlorfon,  and Acetaminophen  on Tumor Progression  in a Fischer  Rat Leukemia  Transplant Model. Cancer Detection  and Prevention  16:173-183.  

Lucier GW, Clark G, Tritscher  A, Foley J, and Maronpot  R, 1992. Mechanisms  of Dioxin Tumor Promotion  - Implications  for Risk Assessment.  Chemosphere  25:177-180.  

Xu YH, Dragan  YP, Maronpot  RR, Goldsworthy  TL, and Pitot HC, 1992. Criteria,  Mechanisms,  and Potency  Evaluation  for Tumor Promoters:  Dioxin as a Model. Chemosphere  25:227-230.  

Dragan  YP, Xu YH, Goldsworthy  TL, Campbell  HA, Maronpot  RR, and Pitot HC, 1992. Characterization   of the Promotion  of Altered  Hepatic  Foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin  in the Female  Rat. Carcinogenesis  13:1389-1395.  

Takahashi  K, Maita K, Kuwahara  M, Harada  T, and Maronpot  RR, 1992. Eosinophilic  Globule  Cells in Mouse MFH-like  Sarcomas:  Lectin Histochemistry.  Virchows  Archiv B Cell Pathol. 62:89-95.

Stanley  LA, Devereux  TR, Foley J, Lord PG, Maronpot  RR, Orton TC, and Anderson  MW, 1992. Proto-oncogene   Activation  in Liver Tumors  of Hepatocarcinogenesis-resistant Strains of Mice. Carcinogenesis  13:2427-2433.  

Anderson  MW, Reynolds  SH, You M, and Maronpot  RR, 1992. Role of Proto-oncogene   Activation in Carcinogenesis.   EHP 98:13-24.  

Cullen JM, Sandgren  EP, Brinster  RL, and Maronpot  RR, 1993. Histologic  Characterization   of Hepatic  Carcinogenesis  in Transgenic  Mice Expressing  SV40 T-antigens.  Vet. Path. 30:111-118.  

Melnick RL, Huff J, Barrett JC, Maronpot  RR, Lucier G, and Portier CJ, 1993. Cell Proliferation  and Chemical  Carcinogenesis:   A Symposium  Overview.  Molecular  Carcinogenesis  7:135-138.  

Anderson  MW and Maronpot  RR, 1993. Editorial:  Methylene  Chloride-induced   Tumorigenesis. Carcinogenesis  14:787-788.  

Devereux  TR, Foley JF, Maronpot  RR, Kari F, and Anderson  MW, 1993. Ras Proto-oncogene Activation  in Liver and Lung Tumors  from B6C3F1  Mice Exposed  Chronically  to Methylene Chloride.  Carcinogenesis  14:795-802.  

Hegi ME, Soderkvist  P, Foley JF, Schoonhoven  R, Swenberg  JA, Kari F, Maronpot  R, Anderson MW, and Wiseman  RW, 1993. Characterization   of p53 Mutations  in Methylene  Chloride-induced Lung Tumors  from B6C3F1  Mice. Carcinogenesis  14:803-810.  

Foley JF, Tuck PD, Ton TVT, Frost M, Kari F, Anderson  M.W, and Maronpot  RR, 1993. Inhalation Exposure  to a Hepatocarcinogenic  Concentration  of Methylene  Chloride  Does Not Induce Sustained  Replicative  DNA Synthesis  in Hepatocytes  of Female  B6C3F1  Mice. Carcinogenesis 14:811-818.  

Kari FW, Foley JF, Seilkop  SK, Maronpot  RR, and Anderson  MW, 1993. Effect of Varying  Exposure Regimens  on Methylene  Chloride-induced   Lung and Liver Tumors  in Female  B6C3F1  Mice. Carcinogenesis  14:819-826.  

Chen B, Liu L, Castonguay  A, Maronpot  RR, Anderson  MW, and You M, 1993. Dose-dependent   ras Mutation  Spectra  in N- nitrosodiethylamine-induced Mouse Liver Tumors  and 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone  Induced  Mouse Lung Tumors.  Carcinogenesis 14:1603-1608.  

Devereux  TR, Belinsky  SA, Maronpot  RR, White CM, Hegi ME, Patel AC, Foley JF, Greenwell  A, and Anderson  MW, 1993. Comparison  of Pulmonary  06-methylguanine   DNA Adduct Levels and Ki- ras Activation  in Lung Tumors  from Resistant  and Susceptible  Mouse Strains.  Molecular Carcinogenesis  8:177-185.  

Maronpot  RR, Foley JF, Takahashi  K, Goldsworthy  T, Clark G, Tritscher  A, Portier C, and Lucier G, 1993. Dose Response  for TCDD Promotion  of Hepatocarcinogenesis  in Rats Initiated  with DEN: Histologic,  Biochemical,  and Cell Proliferation  Endpoints.  EHP 101:634-642.  

Johnson  GA, Benveniste  H, Black RD, Hedlund  LW, Maronpot  RR, and Smith BR, 1993. Histology  by Magnetic  Resonance  Microscopy.  Magnetic  Resonance  Quarterly  1993; 9(1):1-30.  

Kanno J, Maronpot  RR, Takahashi  M, Kasuga  T, and Hayashi  Y, 1993. Regressive  and Non- regressive  Thyroid  Lesions  of the Rat Induced  by Single Injection  of N-bis(2-hydroxypropyl) nitrosamine  and Iodine Deficient  Diet. Carcinogenesis  14:2389-2396.  

Melnick RL, Huff J, Barrett JC, Maronpot  RR, Lucier G, and Portier CJ, 1993. Cell Proliferation  and Chemical  Carcinogenesis:  Symposium  Overview.  EHP 101:3-5.   Goldsworthy  TL, Butterworth  BE, and Maronpot  RR, 1993. Concepts,  Labeling  Procedures,  and Design of Cell Proliferation  Studies  Relating  to Carcinogenesis.  EHP 101:59-65.

Foley J, Ton T, Maronpot  R, Butterworth  B, and Goldsworthy  TL, 1993. Comparison  of Proliferating Cell Nuclear  Antigen  to Tritiated  Thymidine  as a Marker of Proliferating  Hepatocytes  in Rats. EHP 101:199-205.  

Greenwell  A, Foley JF, and Maronpot  RR, 1993. Detecting  Proliferating  Cell Nuclear  Antigen  in Archival  Rodent Tissues.  EHP 101:207-209.  

Kanno J, Foley JF, Kari F, Anderson  MW, and Maronpot  RR, 1993. Effect of Methylene  Chloride Inhalation  on Replicative  DNA Synthesis  in the Lungs of Female  B6C3F1  Mice. EHP 101:271-276.  

Ghanayem  BI, Sanchez  IM, Maronpot  RR, Elwell MR, and Matthews  HB, 1993. Relationship Between  the Time of Sustained  Ethyl Acrylate  Forestomach  Hyperplasia  and Carcinogenicity.   EHP 101:277-280.  

Takahashi  K, Lindamood  III C, and Maronpot  RR, 1993. Retrospective  Study of Possible  a-2m- globulin  Nephropathy  and Associated  Cell Proliferation  in Male Fischer  344 Rats Dosed with t-butyl alcohol.  EHP 101:281-286.  

Herzog  CR, Schut HAJ, Maronpot  RR, and You M, 1993. Ras Mutations  in 2-amino-3- methylimidazo[4,5-f]quinoline-induced  Tumors  from the CDF1 Mouse.  Molecular  Carcinogenesis 8:202-207.  

Cunningham  ML, Maronpot  RR, Thompson  M, and Bucher JR, 1994. Early Responses  of the Liver of B6C3F1  Mice to the Hepatocarcinogen   Oxazepam:  Tox. & Appl. Pharmacol.  124:31-38  

Dixon D, Yoshitomi  K, Boorman  GA, and Maronpot  RR, 1994. “Lipomatous”  Lesions  of Unknown Cellular  Origin in the Liver of B6C3F1  Mice. Vet.. Path. 31:173-182.  

Devereux  TR, White CM, Sills RC, Bucher JR, Maronpot  RR, and Anderson  MW, 1994. Low Frequency  of H-ras Mutations  in Hepatocellular  Adenomas  and Carcinomas  and in Hepatoblastomas   from B6C3F1  Mice Exposed  to Oxazepam  in the Diet. Carcinogenesis  15:1083- 1087.  

Zhou X, Maronpot  RR, Mills GI, Cofer GP, Hedlund  LW and Johnson  GA, 1994: Studies  on Bromobenzene-induced  Hepatotoxicity  Using in vivo MR Microscopy  with Surgically  Implanted  RF Coils. Magnetic  Resonance  in Medicine  31:619-627.  

Stanley  LA, Blackburn  DR, Devereaux  S, Foley J, Lord PG, Maronpot  RR, Orton TC, and Anderson MW, 1994. Ras Mutations  in Methylclofenapate-induced B6C3F1  and C57BL/10J  Mouse Liver Tumours.  Carcinogenesis  15:1125-1131.  

Boorman  GA, Maronpot  RR, and Eustis SL, 1994. Rodent Carcinogenicity  Bioassay:  Past, Present, and Future. Tox. Path. 22:105-111.  

Preston  GA, Lang JE, Maronpot  RR, and Barrett JC, 1994. Regulation  of Apoptosis  by Low Serum in Cells of Different  Stages of Neoplastic  Progression:  Enhanced  Susceptibility  After Loss of a Senescence  Gene and Decreased  Susceptibility  After Loss of a Tumor Suppressor  Gene. Cancer Res. 54:4214-4223.  

Anna CH, Maronpot  RR, Pereira  MA, Foley JF, Malarkey  DE, and Anderson  MW, 1994. Ras Proto- oncogene  Activation  in Dichloroacetic  acid-, Trichloroethylene-,and  Tetrachloroethylene-induced Liver Tumors  in B6C3F1  Mice. Carcinogenesis  15:2255-2261.  

Davis BJ, Maronpot  RR, and Heindel  JJ, 1994. Di-(2-ethylhexyl)   Phthalate  Suppresses  Estradiol and Ovulation  in Cycling  Rats. Tox. & Appl. Pharmacol.  128:216-223.  

Goodrow  TL, Nichols  WW, Storer RD, Anderson  MW, and Maronpot  RR, 1994. Activation  of H-ras is Prevalent  in 1,3-Butadiene-induced  and Spontaneously  Occurring  Murine Harderian  Gland Tumors.  Carcinogenesis  15:2665-2667.

Hegi ME, Devereux  TR, Dietrich  WF, Cochran  CJ, Lander ES, Foley JF, Maronpot  RR, Anderson MW, and Wiseman  RW, 1994. Allelotype  Analysis  of Mouse Lung Carcinomas  Reveals  Frequent Allelic Losses on Chromosome  4 and an Association  Between  Allelic Imbalances  on Chromosome 6 and K-ras activation.  Cancer Res. 54:6257-6264.  

Devereux  TR, Wiseman  RW, Kaplan  N, Garren  S, Foley JF, White CM, Anna C, Watson  MA, Patel A, Jarchow  S, Maronpot  RR, and Anderson  MW, 1994. Assignment  of a Locus for Mouse Lung Tumor Susceptibility  to Proximal  Chromosome  19. Mammalian  Genome  5:749-755.  

Davis LM, Caspary  WJ, Sakallah  SA, Maronpot  R, Wiseman  R, Barrett JC, Elliott R, and Hozier JC, 1994. Loss of Heterozygosity  in Spontaneous  and Chemically  induced  Tumors  of the B6C3F1 Mouse.  Carcinogenesis  15:1637-1645.  

Sewall CH, Flagler N, Vanden  Heuvel JP, Clark GC, Tritscher  AM, Maronpot  RR, and Lucier GW, 1995. Alterations  in Thyroid  Function  in Female  Sprague-Dawley   Rats Following  Chronic  Treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin.  Tox. & Appl. Pharmacol.  132:237-244.  

Ton TT, Elwell MR, Morris RW, and Maronpot  RR, 1995. Development  and Persistence  of Placental  Glutathione-S-Transferase-positive  Foci in Livers of Male F344 Rats Exposed  to o- Nitrotoluene.  Cancer Ltrs. 95:167-173.  

Watson  MA, Devereux  TR, Malarkey  DE, Anderson  MW, and Maronpot  RR, 1995. H-ras Oncogene Mutation  Spectra  in B6C3F1  and C57BL/6  Mouse Liver Tumors  Provide  Evidence  for TCDD Promotion  of Spontaneous  and Vinyl Carbamate-initiated  Liver Cells. Carcinogenesis  16:1705- 1710.  

Maronpot  RR, Fox T, Malarkey  DE, and Goldsworthy  TL, 1995. Mutations  in the ras Proto- oncogene:  Clues to Etiology  and Molecular  Pathogenesis  of Mouse Liver Tumors.  Toxicology 101:125-156.  

Massey  TE, Devereux  TR, Maronpot  RR, Foley JF, and Anderson  MW, 1995. High Frequency  of K- ras Mutations  in Spontaneous  and Vinyl Carbamate-induced  Lung Tumors  of Relatively  Resistant B6CF1  (C57BL/6J  x BALB/cJ)  Mice. Carcinogenesis  16:1065-1069.  

Takahashi  K, Vivano CJ, Elwell MR, Bakewell  WE, Kuwahara  M, Nakashima  N, Blackwell  BN, and Maronpot  RR, 1995. Bile Duct-specific  Lectins,  Dolichos  Biflorus  agglutinin  and peanut agglutinin, as Probes in Mouse Hepatocarcinogenesis.  Laboratory  Investigation  73:424-432.  

Maronpot  RR, Devereux  TR, Hegi M, Foley JF, Kanno J, Wiseman  R, and Anderson  MW, 1995. Hepatic  and Pulmonary  Carcinogenicity  of Methylene  Chloride  in Mice: A Search for Mechanisms. Toxicology  102:73-81.  

Malarkey  DE, Devereux  TR, Dinse GE, Mann PC, and Maronpot  RR, 1995. Hepatocarcinogenicity of Chlordane  in B6C3F1  and B6D2F1  Male Mice: Evidence  for Regression  in B6C3F1  Mice and Carcinogenesis  Independent  of ras Proto-oncogene   Activation.  Carcinogenesis  16:2617-2625.  

Liu J, Phillips KW, Foley JF, and Maronpot  RR, 1995. Optimizing  in situ Hybridization  of Lactoferrin mRNA in Mouse Uterine  Tissue Using Digoxigenin-labeled  RNA Probes.  Cell Vision 2:430-434.  

Zhou X, Maronpot  RR, Hedlund  LW, Cofer GP, and Johnson  GA, 1995. Detection  of Bromobenzene-induced  Hepatocellular  Necrosis  Using Magnetic  Resonance  Microscopy.  Magnetic Resonance  in Medicine  34:853-857.  

Tritscher  AM, Clark GC, Sewall CS, Sills RC, Maronpot  R, and Lucier GW, 1995. Persistence  of TCDD-induced  Hepatic  Cell Proliferation  and Growth  of Enzyme  Altered  Foci After Chronic Exposure  Followed  by Cessation  of Treatment  in DEN Initiated  Female  Rats. Carcinogenesis 16:2807-2811.  

Malarkey  DE and Maronpot  RR, 1996. Polymerase  Chain Reaction  and in situ Hybridization: Applications  in Toxicological  Pathology.  Tox. Path. 24:13-23.    

Goldsworthy  TL, Fransson-Steen   R, and Maronpot  RR, 1996. Importance  of and Approaches  to Quantification  of Hepatocyte  Apoptosis.  Tox. Path. 24:24-35.  

Delnomdedieu  M, Hedlund  LW, Johnson  GA, and Maronpot  RR, 1996. Magnetic  Resonance Microscopy  -- A New Tool for the Toxicologic  Pathologist.  Tox. Path. 24:36-44.  

Portier   CJ, Sherman  CD, Kohn M, Edler L, Kopp-Schneider   A, Maronpot  RR and Lucier G, 1996. Modeling  the Number  and Size of Hepatic  Focal Lesions  Following  Exposure  to 2,3,7,8-TCDD. Toxicol.  Appl. Pharmacol.  138:20-30.  

Maronpot  RR. 1996. Editorial.  Laboratory  Animal Pathology  - Emphasis  on an Area of Relevance  to the Toxicologic  Pathologist.   Tox. Path. 24: 506.

  Mahler JF, Stokes W,Mann  PC,Takaoka  M and Maronpot  RR. 1996. Spontaneous  Lesions  in Aging FVB/N Mice. Tox. Path. 24: 710-716.  

Maronpot  RR. 1996.  A Symposium  Summary  and Perspective  on Comparative  Molecular  Biology of Cancer.  Tox. Path. 24: 801-804.  

Maronpot  RR and Boorman  GA. 1996. The Contribution  of the Mouse in Hazard  Identification Studies.  Tox. Path. 24: 726-733.  

Carthew  P, Maronpot  RR, Foley J, Edwards,  RE and Dorman,BM.  1996.  A Method  for Determining Whether  the Number  of Hepatocytes  in Rat Liver is Increased  after Treatment  with the Peroxisome Proliferator  Gemfibrozil.   J. Appl. Toxicol.  17: 47-51.  

Donnelly,  PJ, Devereux,  TR, Foley, JF, Maronpot,  RR, Anderson,  MW and Massey,  TE.  1996. Activation  of K-ras in Aflatoxin  B1-Induced  Lung Tumors  from AC3F1  (A/J x C3H/HeJ)  Mice. Carcinogenesis  17: 1735-1740.  

Albert, RE, French,  JF, Maronpot,  R, Spalding,  J and Tennant,  R.  1996.  Mechanisms  of Skin Tumorigenesis  by contact Sensitizers:  The Effect of the corticosteroid  Fluocinolone  Acetonide  on Inflammation  and Tumor Induction  by 2,4 Dinitro-1-fluorobenzene  in the Skin of the TG.AC (v-Ha- ras) Mouse.   Environ.  Hlth. Persp. 104: 1062-1068.  

Kong, L-Y, McMillian,  MK, Maronpot,  R, Hong, J-S. 1996.  Protein  tyrosine  kinase inhibitors suppress  the production  of nitric oxide in mixed glia, microglia-enriched   or astrocyte-enriched cultures.   Brain Res. 729: 102-109.  

Davis,  BJ, Almekinder,  JL, Flagler,  N, Travlos,  G, Wilson,  R, and Maronpot,  RR.   1997.   Ovarian Luteal Cell Toxicity  of Ethylene  Glycol Monomethyl  Ether and Methoxy  Acetic Acid in Vivo and in Vitro.  Toxicol.  Appl. Pharmacol.   142: 328-337.  

Fox, TR, McMillen,  PJ, Maronpot,  RR and Goldsworthy,  TL.  1997.  Genomic  Instability,  as Measured  by Microsatellite  Alterations,  Is Not Associated  with Liver Tumor Development  in the Genetically  Susceptible  B6C3F1  Mouse.   Toxocol.  Appl. Pharmacol.  143: 167-172.  

Witschi,  H, Espiritu,  I, Peake, JL, Wu, K, Maronpot,  RR and Pinkerton,  KE.  1997.  The Carcinogenicity  of Environmental  Tobacco  Smoke.   Carcinogenesis  18: 575-586.  

Fransson-Steen,   R, Goldsworthy,  TL, Kedderis,  GL and Maronpot,  RR.  1997.  Furan-induced  liver cell proliferation  and apoptosis  in female B6C3F1  mice.  Toxicology  118: 195-204.  

Johansson,  E, Reynolds,  S, Anderson,  M and Maronpot,  R.  1997.  Frequency  of Ha-ras-1  Gene Mutations  Inversely  Correlated  with Furan Dose in Mouse Liver Tumors.   Mol. Carcinogenesis  18: 199-205.  

Romach,  EH, Goldsworthy,  TL, Maronpot,  RR and Fox, TR.  1997.  Altered  gene expression  in spontaneous  hepatocellular  carcinomas  from male B6C3F1  mice.  Mol. Carcinogenesis  19: 31-38.  

Carthew  P, Maronpot  RR, Foley JF, Edwards  RE, and Nolan BM,  1997. Method  for determining whether  the number  of hepatocytes  in rat liver is increased  after treatment  with the peroxisome proliferator  gemfibrozil.  J Appl Toxicol.  17: 47-51.  

Maronpot  RR,  1997. Comments  on the medium-term  rat liver focus bioassay.  Toxicol Pathol. 25: 461.  

Witschi H, Espiritu  I, Peake JL, Wu K, Maronpot  RR, and Pinkerton  KE,  1997. The carcinogenicity of environmental  tobacco  smoke. Carcinogenesis.  18: 575-586.  

Kim, T-W, Porter, KL, Foley, JF, Maronpot,  RR and Smart, RC. 1997. Evidence  that mirex promotes  a unique population  of epidermal  cells that cannot be distinguished  by their mutant Ha- ras genotype.   Mol. Carcinogenesis  20: 115-124.  

Mitsumori,  K, Wakana,  S, Yamamoto,  S, Kodama,  Y, Yasuhara,  K, kNomura,  T, Hayashi,  Y and Maronpot,  RR. 1997.  Susceptibility  of Transgenic  Mice Carrying  Human  Prototype  c-Ha-ras  Gene in a Short-Term  Carcinogenicity  Study of Vinyl Carbamate  and ras Gene Analyses  of the Induced Tumors.   Molecular  Carcinogenesis  20: 298-307.  

Witschi,  H, Espiritu,  I, Maronpot,  RR, Pinkerton,  KE and Jones, AD.  1997.  The Carcinogenic Potential  of the Gas Phase of Environmental  Tobacco  Smoke.   Carcinogenesis  18: 2035-2042.  

Ton, TT, Foley, JF, Flagler,  ND, Gaul, BW and Maronpot,  RR.  1997.  Feasibility  of Administering  5- Bromo-2’-Deoxyuridine  (BRDU)  in Drinking  Water for Labeling  S-Phase  Hepatocytes  in Rats and Mice.  Toxicol.  Methods  7: 123-136.  

Nyska A, Maronpot  RR, Eldridge  SR, Haseman  JK and Hailey JR.  1997.  Alteration  in Cell Kinetics in Control B6C3F1  Mice Infected  with Helicobacter  hepaticus.   Toxicol.  Pathol. 25: 591-596.  

Delnomdedieu  M, Hedlund  LW, Maronpot  RR and Johnson  GA.  1998.  Magnetic  Resonance Microscopy  and Histopathology:  Comparative  approach  of bromobenzene-Induced  Hepatotoxicity in the Rat.  Hepatology  27: 526-532.  

Nyska A, Leininger  JR, Maronpot  RR, Haseman  JK and Hailey JR.  1998.  Effect of Individual Versus Group Caging  on the Incidence  of Pituitary  and Leydig Cell Tumors  in F344 Rats: Proposed Mechanism.   Med. Hypotheses  50: 525-529.  

Enomoto  A, Sandgren  EP and Maronpot,  RR.   1998.   Interactive  Effects  of c-myc and Transforming Growth  Factor  a Transgenes  on Liver Tumor  Development  in Simian  Virus 40 T Antigen  Transgenic Mice.  Vet. Pathol. 35: 283-291.  

Dragan  Y, Klaunig  J, Maronpot  R, and Goldsworthy  T,  1998. Mechanisms  of susceptibility  to mouse liver carcinogenesis.  Toxicol Sci. 41: 3-7.  

Nyska A, Leininger  JR, Maronpot  RR, Haseman  JK, and Hailey JR,  1998. Effect of individual versus group caging on the incidence  of pituitary  and Leydig cell tumors in F344 rats: proposed mechanism.  Med Hypotheses.  50: 525-529.  

Maronpot  RR.  1998.  The Potential  of Genetically  Altered  Mice as Animal Models for Carcinogen Identification.   Toxicol.  Pathol. 26: 579-581.  

Enomoto  A, Sandgren  EP and Maronpot  RR.  1998.  Altered  Differentiation  of Hepatocytes  in a Transgenic  Mouse Model of Hepatocarcinogenesis.   Toxicol.  Pathol. 26: 570-578.  

Hailey JR, Haseman  JK, Bucher JR, Radovsky  AE, Malarkey  DE, Miller RT, Nyska A and Maronpot RR.  1998.  Impact of Helicobacter  hepaticus  Infection  in B6C3F1  Mice from Twelve National Toxicology  Program  Two-Year  Carcinogenesis  Studies.   Toxicol.  Pathol. 26: 602-611.  

Nyska A, Maronpot  RR, Long PH, Roycroft  JH, Hailey JR, Travlos GS and Ghanayem  BI.  1999. Disseminated  Thrombosis  and Bone Infarction  in Female  Rats Following  Inhalation  Exposure  to 2- Butoxyethanol.   Toxicol.  Pathol. 27: 21-28.  

Chhabra  RS, Maronpot,  RR, Bucher,  JR, Haseman,  JK, Toft, JD and Hejtmancik,  MR.  1999. Toxicology  and Carcinogenesis  Studies  of Pentachlorophenol  in Rats.  Toxicol.  Sci. 48: 14-20  

Johnson  J, Murray PK and Maronpot  RR.  1999.  Improved  Method  for Ultrastructural  Preservation of Saccharomyces   cerevisiae  JHY-31-11D.   Applied  Immunohistochem and Molecular  Morphology 7: 81-86.  

Goldsworthy  SM, Stockton  PS, Trempus  CS, Foley JF and Maronpot  RR.  1999.  Effects of Fixation on RNA Extraction and Amplification  from Laser Capture  Microdissected  Tissue. Mol.Carc. 25:86-91.  

Nyska A, Haseman  JK, Hailey JR, Smetana  S and Maronpot  RR. 1999. The Association Between Severe  Nephropathy  and Pheochromocytoma  in the Male F344 Rat - The National  Toxicology Program  Experience.   Toxicol.  Pathol. 27: 456-462.  

Levin S, Bucci TJ, Cohen SM, Fix AS, Hardisty  JF, LeGrand  EK, Maronpot  RR and Trump BF. 1999. The Nomenclature  of Cell Death: Recommendations  of an ad hoc Committee  of the Society of Toxicologic  Pathologists.   Toxicol.  Pathol. 27: 484-490.  

Tam AS, Foley JF, Devereux  TR, Maronpot  RR and Massey  TE.  1999.  High Frequency and Heterogeneous  Distribution  of p53 Mutations  in Aflatoxin  B1-induced  Mouse Lung Tumors.   Cancer Res. 59: 3634-3640.  

Nyska A, Maronpot  RR and Ghanayem  BI.  1999.  Ocular thrombosis and retinal degeneration induced  in female F344 rats by 2-butoxyethanol.    Human  & Experimental  Toxicology  18: 577-582.  

Witschi H, Espirtu  I, Pinkerton  KE, Murphy  K and Maronpot  RR. 1999. Ozone Carcinogenesis Revisited.  Toxicol.  Sci. 52: 162-167.  

Ma J, Qu W, Scarborough  PE, Tomer  KB, Moomaw  CR, Maronpot,  R, Davis  LS, Breyer  MD and Zeldin  DC.   1999.  Molecular  cloning,  enzymatic  characterization,   developmental   expression,  and cellular localization  of a mouse cytochrome  P450 highly expressed  in kidney.   J. Biol. Chem. 274: 17777-17788.  

Long PH, Maronpot  RR, Ghanayem  BI, Roycroft  JH and Myska A.  2000.  Dental Pulp Infarction  in Female  Rats Following  Inhalation  Exposure  to 2-Butoxyethanol.    Toxicol.  Pathol. 28: 246-252.  

Maronpot  RR. 2000. The use of genetically  modified  animals  in carcinogenicity  bioassays.   Toxicol. Pathol. 28: 450-453  

Maronpot  RR, Mitsumori  K, Mann P, Takaoka  M, Yamamoto  S, Usui T, Okamiya  H, Nishikawa  S and Nomura  T.  2000. Interlaboratory  comparison  of the CB6F1-Tg  rasH2 rapid carcinogenicity testing model.   Toxicology  146: 149-159.  

Chen XJ, Hedlund  LW, Moller HE, Chawla  MS, Maronpot  RR and Johnson  GA.  2000.  Detection  of emphysema  in rat lungs by using magnetic  resonance  measurements  of 3He diffusion.   PNAS 97:11478-11481.  

Liomnitski  L, Foley JF, Grossman  S, Shaul VB, Maronpot  RR, Moomaw  CR, Carbonatto  M and Nyska A.  2000. Effects of apocynin  and natural antioxidant  from spinach  on inducible  nitric oxide synthase  and cyclooxygenase-2   induction  in lipoipolysaccharide-induced hepatic  injury in rat. Pharmacology  & Toxicology  87: 18-25.  

Lomnitski  L, Carbonatto  M, Ben-Shaul  V, Peano  S, Conz A, Corradin  L, Maronpot  RR, Grossman S, and Nyska  A,  2000. The prophylactic  effects  of natural  water-soluble  antioxidant  from spinach and apocynin  in a rabbit model of lipopolysaccharide-induced endotoxemia.  Toxicol Pathol. 28: 588-600.  

Lomnitski  L, Nyska A, Ben-Shaul  V, Maronpot  RR, Haseman  JK, Harrus TL, Bergman  M, and Grossman  S,  2000. Effects of antioxidants  apocynin  and the natural water-soluble  antioxidant from spinach  on cellular damage  induced  by lipopolysaccaride   in the rat. Toxicol Pathol. 28: 580-587.    

Maronpot  RR, Mitsumori  K, Mann P, Takaoka  M, Yamamoto  S, Usui T, Okamiya  H, Nishikawa  S, and Nomura  T,  2000. Interlaboratory  comparison  of the CB6F1-Tg  rasH2 rapid carcinogenicity testing model. Toxicology.  146: 149-159.  

Sabo T, Lomnitski  L, Nyska A, Beni S, Maronpot  RR, Shohami  E, Roses AD, and Michaelson DM,  2000. Susceptibility  of transgenic  mice expressing  human apolipoprotein  E to closed head injury: the allele E3 is neuroprotective  whereas  E4 increases  fatalities.  Neuroscience.  101: 879-884.  

Tsao CC, Foley J, Coulter SJ, Maronpot  R, Zeldin DC, and Goldstein  JA,  2000. CYP2C40,  a unique arachidonic  acid 16-hydroxylase,  is the major CYP2C  in murine intestinal  tract. Mol Pharmacol.  58: 279-287.  

Suwa, T., Nyska, A., Peckham,  JC, Hailey, JR, Mahler,  JF, Haseman,  JK and Maronpot,  RR. 2001.  A retrospective  analysis  of background  lesions and tissue accountabiity  for male accessory  sex organs in Fischer-344  rats.  Toxicol.  Pathol. 29: 467-478.  

Suwa, T., Nyska, A, Haseman,  JK, Mahler,  JF and Maronpot,  RR. 2001.  Spontaneous  lesions in control B6C3F1  mice and recommended  section of male accessory  sex organs.   Toxicol.  Pathol.30:228-234.  

Nyska A, Lomnitski  L, Maronpot  R, Moomaw  C, Brodsky  B, Sintov A, and Wormser  U (2001). Effects of iodine on inducible  nitric oxide synthase  and cyclooxygenase-   2 expression  in sulfur mustard-induced   skin. Arch Toxicol   74: 768-74.  

Qu W, Bradbury  JA, Tsao CC, Maronpot  R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg  RL, and Zeldin DC (2001). Cytochrome  P450 CYP2J9,  a new mouse arachidonic  acid omega-1  hydroxylase  predominately  expressed  in brain. J Biol Chem   276 (27): 25467-79  

Johnson  GA, Cofer GP, Hedlund  LW, Maronpot  RR and Suddarth  SA. 2001. Registered  1H and 3He Magnetic  Resonance  Microscopy  of the Lung.  Magnetic  Resonance  in Med. 45: 365-370.  

Hayashi  S, Hong HH, Toyoda  K, Ton TV, Devereux  TR, Maronpot  RR, Huff J, and Sills RC (2001). High frequency  of ras mutations  in forestomach  and lung tumors of B6C3F1  mice exposed  to 1-amino-2,4-dibromoanthraquinone  for 2 years. Toxicol Pathol   29: 422-9.  

Torres-Munoz  J, Stockton  P, Tacoronte  N, Roberts  B, Maronpot  RR, and Petito CK (2001). Detection  of HIV-1 gene sequences  in hippocampal  neurons  isolated  from postmortem  AIDS brains by laser capture  microdissection.   J Neuropathol  Exp Neurol   60: 885-92.  

Tsao C, Coulter SJ, Chien A, Luo G, Clayton  N, Maronpot  R, Goldstein  JA and Zeldin DC. 2001. Identification  and localization  of five CYP2Cs  in murine extrahepatic  tissues and their metabolism  of arachidonic  acid to regio- and stereoselective  products.   J. Pharmacol.  Exp. Therap.  299: 39-47.  

Gottschling  BC, Maronpot  RR, Hailey JR, Peddada  S, Moomaw  CR, Klaunig  JE and Nska A. 2001. The role of oxidative  stress in indium  phosphide-induced  lung carcinogenesis  in rats. Toxicol Sci 64: 28-40.  

Suwa T, Nyska A, Haseman  JK, Mahler JF and Maronpot  RR.  2002. Spontaneous  lesions in control B6C3F1  mice and recommended  sectioning  of male accessory  sex organs.   Toxicol Pathol 30: 228-234.  

Ozaki K, Haseman  JK, Hailey JR, Maronpot  RR and Nyska A.  2002. Association  of adrenal pheochhromocytoma  and lung pathology  in inhalation  studies with particulate  compounds  in the male F344 rat – The National  Toxicology  Program  experience.   Toxicol Pathol 30: 263-270.  

Nyska A, Dayan A and Maronpot  RR.  2002.  New tools in therapeutic  research  – Prostate  cancer and models.   Toxicol Pathol 30: 283-287.  

Okoji RS, Y RC, Maronpot  RR and Froines  JR.  2002. Sodium  arsenite  administration  via drinking water increases  genome-wide  and Ha-ras DNA hypomethylation   in methyl-deficient  C57BL/6J mice.  Carcinogenesis  23: 777-785.  

Johnson  GA, Cofer GP, Fubara  B, Gewalt SL, Hedlund  LW, and Maronpot  RR (2002). Magnetic resonance histology for morphologic  phenotyping. Magn Reson Imaging   16: 423-9.  

Takahashi  M, Dinse GE, Foley JF, Hardisty  JF, and Maronpot  RR (2002). Comparative prevalence,  multiplicity,  and progression  of spontaneous  and vinyl carbamate-induced  liver lesions in five strains of male mice. Toxicol Pathol   30: 599-605.  

Ma J, Bradbury  JA, King L, Maronpot  R, Davis LS, Breyer MD and Zeldin DC. 2002.  Molecular cloning and characterization  of mouse CYP2J6,  an unstable  cytochrome  P450 isoform.   Biochem Pharmacol  64:1447-1460  

Gallardo-Williams   MT, Maronpot  RR, Wine RN, Brunssen  SH and Chapin  RE.  2003. Inhibition  of the enzymatic  activity of prostate-specific   antigen  by boric acid and 3-nitrophenyl  boronic  acid. The Prostate  54:44-49.  

Tam AS, Devereux  TR, Patel AC, Foley JF, Maronpot  RR and Massey  TR.  2003. Perturbations of the Ink4a/Arf  gene locus in aflatoxin  B1-induced  mouse lung tumors.  Carcinogenesis  24: 121- 132.  

Ress NB, Hailey JR, Maronpot  RR, Bucher JR, Travlos  GS, Haseman  JK, Orzech  DP, Johnson JD and Hejtmancik  MR.  2003. Toxicology  and carcinogenesis  studies of microencapsulated   citral in rats and mice.  Toxicol Sci 71: 198-206.  

Nyska A, Suttie A, Bakshi S, Lomnitski  L, Grossman  S, Bergman  M, Ben-Shaul  V, Crocket  P, Haseman  JK, Moser G, Goldsworthy  TL, and Maronpot  RR. 2003. Slowing  tumorigenic progression  in TRAMP  mice and prostatic  carcinoma  cell lines using natural anti-oxidant  from spinach,  NAO--a  comparative  study of three anti-oxidants.  Toxicol Pathol   31: 39-51.  

Gallardo-Williams   MT, Maronpot  RR, Turner CH, Johnson  CS, Harris MW, Jayo MJ, Chapin  RE. (2003) Effects of boric acid supplementation   on bone histomorphometry,   metabolism,  and biomechanical  properties  in aged female F-344 rats. Biol. Trace Element  Res. 93: 155-169.  

Picut CA, Aoyama  H, Holder JW, Gold LS, Maronpot  RR and Dixon D. (2003). Bromoethane, chloroethane  and ethylene  oxide induced  uterine neoplasms  in B6C3F1  mice from 2-year inhalation  bioassyas:  pathology  and incidence  data revisited.   Exp Toxic Pathol   55: 1-9.  

Gallardo-Williams,   M. T., Maronpot,  R. R., Wine, R. N., Brunssen,  S. H., and Chapin,  R. E. (2003). Inhibition  of the enzymatic  activity of prostate-specific   antigen  by boric acid and 3- nitrophenyl  boronic  acid. Prostate  54: 44-9.  

Calderon-Garciduenas,  L., Maronpot,  R. R., Torres-Jardon,  R., Henriquez-Roldan,  C., Schoonhoven,  R., Acuna-Ayala,  H., Villarreal-Calderon,  A., Nakamura,  J., Fernando,  R., Reed, W., Azzarelli,  B., and Swenberg,  J. A. (2003). DNA damage  in nasal and brain tissues of canines exposed  to air pollutants  is associated  with evidence  of chronic  brain inflammation  and neurodegeneration.  Toxicol Pathol 31, 524-38.  

Gallardo-Williams,   M. T., Maronpot,  R. R., Turner, C. H., Johnson,  C. S., Harris, M. W., Jayo, M. J., and Chapin,  R. E. (2003). Effects of boric acid supplementation   on bone histomorphometry, metabolism,  and biomechanical  properties  in aged female F-344 rats. Biol Trace Elem Res 93, 155-70.  

Crissman,  J. W., Goodman,  D. G., Hildebrandt,  P. K., Maronpot,  R. R., Prater, D. A., Riley, J. H., Seaman,  W. J., and Thake, D. C. (2004). Best practices  guideline:  toxicologic  histopathology. Toxicol Pathol 32, 126-31.  

Gallardo-Williams,   M. T., Chapin,  R. E., King, P. E., Moser,  G. J., Goldsworthy,  T. L., Morrison,  J. P., and Maronpot,  R. R. (2004).  Boron  Supplementation   Inhibits  the Growth  and Local Expression of IGF-1 in Human  Prostate  Adenocarcinoma   (LNCaP)  Tumors  in Nude Mice. Toxicol Pathol 32, 73-8.      

Tani, Y., Maronpot,  R. R., Foley, J. F., Haseman,  J. K., Walker,  N. J., and Nyska, A. (2004). Follicular  Epithelial  Cell Hypertrophy  Induced  by Chronic  Oral Administration  of 2,3,7,8- Tetrachlorodibenzo-p-Dioxin in Female  Harlan Sprague-Dawley   Rats. Toxicol Pathol 32, 41-9.  

Hamadeh,  H. K., Jayadev,  S., Gaillard,  E. T., Huang, Q., Stoll, R., Blanchard,  K., Chou, J., Tucker,  C. J., Collins,  J., Maronpot,  R., Bushel,  P., and Afshari,  C. A. (2004). Integration  of clinical and gene expression  endpoints  to explore  furan-mediated  hepatotoxicity.  Mutat Res 549,169-83.  

Herzog,  C. R., Bodon, N., Pittman,  B., Maronpot,  R. R., Massey,  T. E., Anderson,  M. W., You, M., and Devereux,  T. R. (2004). Carcinogen-specific  targeting  of chromosome  12 for loss of heterozygosity  in mouse lung adenocarcinomas:   implications  for chromosome  instability  and tumor progression.  Oncogene  23, 3033-9.  

Maronpot,  R. R., Flake, G., and Huff, J. (2004). Relevance  of animal carcinogenesis  findings  to human cancer predictions  and prevention.  Toxicol Pathol 32 Suppl 1, 40-8.  

Nikitin, A. Y., Alcaraz,  A., Anver, M. R., Bronson,  R. T., Cardiff, R. D., Dixon, D., Fraire, A. E., Gabrielson,  E. W., Gunning,  W. T., Haines,  D. C., Kaufman,  M. H., Linnoila,  R. I., Maronpot,  R. R., Rabson,  A. S., Reddick,  R. L., Rehm, S., Rozengurt,  N., Schuller,  H. M., Shmidt,  E. N., Travis, W. D., Ward, J. M., and Jacks, T. (2004). Classification  of proliferative  pulmonary  lesions  of the mouse:  recommendations   of the mouse models of human cancers  consortium.  Cancer Res 64, 2307-16.  

Nyska, A., Haseman,  J. K., Kohen, R., and Maronpot,  R. R. (2004). Association  of liver hemangiosarcoma   and secondary  iron overload  in B6C3F1  mice--the  National  Toxicology Program  experience.  Toxicol Pathol 32, 222-8.  

Allen, D. G., Pearse,  G., Haseman,  J. K., and Maronpot,  R. R. (2004). Prediction  of rodent carcinogenesis:  an evaluation  of prechronic  liver lesions as forecasters  of liver tumors in NTP carcinogenicity  studies.  Toxicol Pathol 32, 393-401.  

Sills, R., Morgan,  D., Herr, D., Little, P., George,  N., Ton, T., Love, N., Maronpot,  R., and Johnson,  G. (2004). Contribution  of Magnetic  Resonance  Microscopy  in the 12-Week Neurotoxicity  Evaluation  of Carbonyl  Sulfide in Fischer  344 Rats. Toxicol Pathol 32, 501-510.  

Stumpo,  D. J., Byrd, N. A., Phillips,  R. S., Ghosh, S., Maronpot,  R. R., Castranio,  T., Meyers,  E. N., Mishina,  Y., and Blackshear,  P. J. (2004). Chorioallantoic  fusion defects and embryonic lethality resulting  from disruption  of Zfp36L1,  a gene encoding  a CCCH tandem  zinc finger protein of the Tristetraprolin  family. Mol Cell Biol 24, 6445-55.  

Calderon-Garciduenas,  L., Reed,  W., Maronpot,  R. R., Henriquez-Roldan,  C., Delgado-Chavez, R., Calderon-Garciduenas,  A., Dragustinovis,  I., Franco-Lira,  M., Aragon-Flores,  M., Solt, A. C., Altenburg,  M., Torres-Jardon,  R., and Swenberg,  J. A. (2004). Brain inflammation  and Alzheimer's-like  pathology  in individuals  exposed  to severe air pollution.  Toxicol Pathol 32, 650-8.  

Maronpot,  R. R., Sills, R. C., and Johnson,  G. A. (2004).  Applications  of magnetic  resonance microscopy.  Toxicol Pathol 32 Suppl 2, 42-8.  

Morgan,  D. L., Little, P. B., Herr, D. W., Moser, V. C., Collins,  B., Herbert,  R., Johnson,  G. A., Maronpot,  R. R., Harry, G. J., and Sills, R. C. (2004). Neurotoxicity  of carbonyl  sulfide in F344 rats following  inhalation  exposure  for up to 12 weeks. Toxicol Appl Pharmacol  200, 131-45.  

Moyer, C., Allen, D., Basabe,  A., Maronpot,  R. R., and Nyska, A. (2004). Analysis  of vascular endothelial  growth factor (VEGF)  and a receptor  subtype  (KDR/flk-1)  in the liver of rats exposed to riddelliine:  a potential  role in the development  of hemangiosarcoma.  Exp Toxicol Pathol 55, 455-65.  

Yamamoto,  Y., Moore, R., Goldsworthy,  T. L., Negishi,  M., and Maronpot,  R. R. (2004). The orphan  nuclear  receptor  constitutive  active/androstane   receptor  is essential  for liver tumor promotion  by phenobarbital  in mice. Cancer Res 64, 7197-200.    

Zhou, T., Jia, X., Chapin,  R. E., Maronpot,  R. R., Harris, M. W., Liu, J., Waalkes,  M. P., and Eddy, E. M. (2004). Cadmium  at a non-toxic  dose alters gene expression  in mouse testes. Toxicol Lett 154, 191-200.  

Malarkey,  D.E., Johnson,  K., Ryan, L., Boorman,  G. and Maronpot,  R. R. (2005). New Insights into Functional  Aspects  of Liver Morphology.  Toxicol.  Pathol..  33: 27-34.  

Malarkey,  D.E., Parker, J.S., Turman,  C.A., Scott, A.M., Paules,  R.S., Collins,  J. and Maronpot, R. R. (2005). Microarray  Data Analysis  of Mouse Neoplasia.  Toxicol.  Pathol. 33: 127-135.  

Suttie, A. W., Dinse, G. E., Nyska, A., Moser, G. J., Goldsworthy,  T. L., and Maronpot,  R. R. (2005). An investigation  of the effects of late-onset  dietary restriction  on prostate  cancer development  in the TRAMP  mouse. Toxicol Pathol 33, 386-97.  

Tani, Y., Suttie, A., Flake, G. P., Nyska, A., and Maronpot,  R. R. (2005). Epithelial-stromal   tumor of the seminal  vesicles  in the transgenic  adenocarcinoma   mouse prostate  model. Vet Pathol 42: 306-14.  

Witschi,  H., Espiritu,  I., and Maronpot,  R. R. (2006). Lung tumors in 2 year old strain A/J mice exposed  for 6 months to tobacco  smoke. Cancer Lett. 241: 64-68.  

Tam, N. N., Nyska, A., Maronpot,  R. R., Kissling,  G., Lomnitski,  L., Suttie, A., Bakshi,  S., Bergman, M., Grossman,  S., and Ho, S. M. (2006). Differential  attenuation  of oxidative/nitrosative injuries in early prostatic  neoplastic  lesions in TRAMP  mice by dietary antioxidants.  Prostate  66, 57-69.  

Yamamoto,  Y., Moore, R., Hess, H. A., Guo, G. L., Gonzalez,  F. J., Korach,  K. S., Maronpot,  R. R., and Negishi,  M. (2006). Estrogen  receptor  alpha mediates  17alpha  -ethynylestradiol-causing hepatotoxicity.  J Biol Chem 281:16625-31.   

Johnson,  K., Ryan, L., Davis, J., Elmore,  A., Guenther,  B., Marcus,  J., and Maronpot,  R. R. (2006). Application  of magnetic  resonance  imaging  in developmental  neurotoxicity  testing: a pilot study. Neurotoxicology   27, 846-51.  

Cardiff, R. D., Anver, M. R., Boivin, G. P., Bosenberg,  M. W., Maronpot,  R. R., Molinolo,  A. A., Nikitin, A. Y., Rehg, J. E., Thomas,  G. V., Russell,  R. G., and Ward, J. M. (2006). Precancer  in mice: animal models used to understand,  prevent,  and treat human precancers.  Toxicol Pathol 34, 699-707.  

Maronpot,  R. R. (2006). A monograph  on histomorphologic   evaluation  of lymphoid  organs.  Toxicol Pathol 34, 407-8.   Maronpot,  R. R. (2006). Enhanced  histopathology  of lymphoid  tissues.  Toxicol Pathol 34, 631-3.

Phillips,  J. M., Yamamoto,  Y., Negishi,  M., Maronpot,  R. R. and Goodman,  J. I. (2007)   Orphan  nuclear receptor  constitutive  active/androstane   receptor-mediated   alterations  in DNA methylation  during phenobarbital  promotion  of liver tumorigenesis.  Toxicol Sci. 96: 72-82.    

Guindon,  K. A., Foley, J. F., Maronpot,  R. R., and Massey,  T. E. (2008). Failure of catalase  to protect against aflatoxin  B(1)-induced  mouse lung tumorigenicity.  Toxicol Appl Pharmacol  227, 179-83.  

Dixon, D., Herbert  R. A., Kissling,  G.E., Brix, A.E., Miller, R.A. and Maronpot,  R. R. (2008) Summary  of chemically  induced  pulmonary  lesions in the National  Toxicology  Program  (NTP) Toxicology  and Carcinogenesis  Studies.  Toxicol Pathol 36: 428-39.      

Calderon-Garciduenas,  L., Mora-Tiscareno,   A., Ontiveros,  E., Gomez-Garza,  G., Barragan-Mejia,   G., Broadway,  J., Chapman,  S., Valencia-Salazar,   G., Jewells,  V., Maronpot,  R. R., Henriquez-Roldan,  C., Perez-Guille,  B., Torres-Jardon,  R., Herrit, L., Brooks,  D., Osnaya-Brizuela,   N., Monroy,  M. E., Gonzalez- Maciel, A., Reynoso-Robles,   R., Villarreal-Calderon,  R., Solt, A. C., and Engle, R. W. (2008). Air pollution, cognitive  deficits and brain abnormalities:  A pilot study with children  and dogs. Brain Cogn. 68(2): 117-27.  

Murkunde,  Y.V., Vijayamumar,  K.S., Hemalatha,  K., Maronpot,  R.R., Herbert,  R.A., Armstrong, J.M. and Wells, M.Y. (2008) Brain Lesion in a Wistar Rat. Lab Animal 37(9): 401-4.  

Calderon-Garciduenas,  L., Macias-Parra,  M., Hoffmann,  H. J., Valencia-Salazar,   G., Henriquez-Roldan, C., Osnaya,  N., Monte, O. C., Barragan-Mejia,   G., Villarreal-Calderon,  R., Romero,  L., Granada-Macias, M., Torres-Jardon,  R., Medina-Cortina,   H., and Maronpot,  R. R. (2009). Immunotoxicity  and environment: Immunodysregulation  and systemic  inflammation  in children.  Toxicol Pathol 37, 161-169.  

Moser, G. J., Foley, J., Burnett,  M., Goldsworthy,  T. L., and Maronpot,  R. (2009). Furan-induced dose- response  relationships  for liver cytotoxicity,  cell proliferation,  and tumorigenicity  (furan-induced  liver tumorigenicity).  Exp Toxicol Pathol 61, 101-111.  

Calderon-Garciduenas,  L., Franco-Lira,  M., Henriquez-Roldan,  C., Osnaya,  N., Gonzalez-Maciel,   A., Reynoso-Robles,   R., Villarreal-Calderon,  R., Herritt, L., Brooks,  D., Keefe, S., Palacios-Moreno,   J., Torres-Jardon,  R., Medina-Cortina,   H., Delgado-Chavez,   R., Aiello-Mora,  M., Maronpot,  R. R., and Doty, R. L. (2009). Urban air pollution:  Influences on olfactory  function  and pathology  in exposed  children  and young adults. Exp Toxicol Pathol. Epub 2009/03/20   Moser, G. J., Foley, J., Burnett,  M., Goldsworthy,  T. L., and Maronpot,  R. (2009). Furan-induced dose- response  relationships for liver cytotoxicity, cell proliferation, and tumorigenicity (furan-induced  liver tumorigenicity).  Exp Toxicol Pathol 61, 101-111.  

Maronpot,  R. R., Zeiger, E., McConnell,  E. E., Kolenda-Roberts,   H., Wall, H., and Friedman,  M. A. (2009). Induction of tunica vaginalis  mesotheliomas  in rats by xenobiotics.  Crit Rev Toxicol 39, 512-537.  

Calderon-Garciduenas,  L., Mora-Tiscareno,   A., Gomez-Garza,  G., Carrasco-Portugal   Mdel, C., Perez- Guille, B., Flores-Murrieta,  F. J., Perez-Guille,  G., Osnaya,  N., Juarez-Olguin,  H., Monroy,  M. E., Monroy, S., Gonzalez-Maciel,   A., Reynoso-Robles,   R., Villarreal-Calderon,  R., Patel, S. A., Kumarathasan,  P., Vincent,  R., Henriquez-Roldan,  C., Torres-Jardon,  R., and Maronpot,  R. R. (2009). Effects of a cyclooxygenase-2   preferential inhibitor  in young healthy dogs exposed  to air pollution:  A pilot study. Toxicol Pathol 37, 644-660.  

Yoshizawa,  K., Jelezcova,  E., Brown, A. R., Foley, J. F., Nyska, A., Cui, X., Hofseth,  L. J., Maronpot,  R. M., Wilson,  S. H., Sepulveda,  A. R., and Sobol, R. W. (2009). Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. PLoS One 4, e6493.  

Arias-Loza,  P. A., Muehlfelder,  M., Elmore,  S. A., Maronpot,  R., Hu, K., Blode, H., Hegele-Hartung,   C., Fritzemeier,  K. H., Ertl, G., and Pelzer, T. (2009). Differential effects of 17b -estradiol  and of synthetic progestins  on aldosterone-salt   induced  kidney disease.  Toxicol Pathol. 37(7):969-82.  

Maronpot, R. R. (2009). Biological basis of differential susceptibility to hepatocarcinogenesis among mouse strains.  J Toxicol Pathol 22, 11-33.  

Branca,  R. T., Cleveland,  Z. I., Fubara,  B., Kumar,  C. S., Maronpot,  R. R., Leuschner,  C., Warren,  W. S., and Driehuys,  B. (2010).  Molecular MRI for sensitive  and specific  detection  of lung metastases.  Proc Natl Acad Sci U S A. 107(8): 3693-7.    

Ghosh,  S., Hoenerhoff,  M. J., Clayton,  N., Myers,  P., Stumpo,  D. J., Maronpot,  R. R., and Blackshear,  P. J. Left-sided  cardiac  valvulitis  in  tristetraprolin-deficient   mice:  The  role  of  tumor  necrosis  factor  alpha. (2010) Am J Pathol 176, 1484-1493.  

Calderon-Garciduenas,  L., Franco-Lira,  M., Henriquez-Roldan,   C., Osnaya,  N., Gonzalez-Maciel,   A., Reynoso-Robles,   R., Villarreal-Calderon,  R., Herritt, L., Brooks,  D., Keefe, S., Palacios-Moreno,   J., Torres-Jardon,  R., Medina-Cortina,   H., Delgado-Chavez,   R., Aiello-Mora,  M., Maronpot,  R. R., and Doty, R. L. ( 2010). Urban air pollution:  influences on olfactory  function  and pathology  in exposed  children  and young adults. Exp Toxicol Pathol 62, 91-102.  

Rodricks,  J. V., Swenberg,  J. A., Borzelleca,  J. F., Maronpot,  R. R., and Shipp, A. M. Triclosan:  A critical review of the experimental  data and development  of margins  of safety for consumer  products.  Crit Rev Toxicol 40, 422-484.  

Botts, S., Ennulat,  D., Francke-Carroll,  S., Graham,  M., Maronpot,  R. R., and Mohutsky,  M. (2010). Introduction to hepatic drug metabolizing enzyme induction in drug safety evaluation studies.  Toxicol Pathol 38, 796-798.  

Maronpot, R. R., Yoshizawa,  K., Nyska, A., Harada,  T., Flake, G., Mueller,  G., Singh, B., and Ward, J. M. (2010). Hepatic enzyme induction:  Histopathology.  Toxicol Pathol 38, 776-795.

Bach, U., Hailey, J. R., Hill, G. D., Kaufmann,  W., Latimer,  K. S., Malarkey,  D. E., Maronpot,  R. M., Miller, R. A., Moore, R. R., Morrison,  J. P., Nolte, T., Rinke, M., Rittinghausen,  S., Suttie, A. W., Travlos,  G. S., Vahle, J. L., Willson,  G. A., and Elmore,  S. A. (2010). Proceedings of the 2009 National Toxicology Program Satellite Symposium.  Toxicol Pathol 38, 9-36.  

Boorman,  G. A., Wolf, D. C., Francke-Carroll,   S., and Maronpot,  R. R. (2010). Pathology peer review.. Toxicol Pathol 38, 1009-1010.  

Thoolen,  B., Maronpot,  R. R., Harada,  T., Nyska, A., Rousseaux,  C., Nolte, T., Malarkey,  D. E., Kaufmann,  W., Kuttler, K., Deschl, U., Nakae, D., Gregson,  R., Vinlove,  M. P., Brix, A. E., Singh, B., Belpoggi,  F., and Ward, J. M. (2010). Proliferative and nonproliferative  lesions of the rat and mouse hepatobiliary  system.  Toxicol Pathol 38, 5S-81S.  

Villarreal-Calderon,  R., Torres-Jardon,  R., Palacios-Moreno,   J., Osnaya,  N., Perez-Guille,  B., Maronpot, R. R., Reed, W., Zhu, H., and Calderon-Garciduenas,  L. (2010). Urban air pollution targets the dorsal vagal complex  and dark chocolate  offers neuroprotection.  Int J Toxicol 29, 604-615.  

Adams,  E. T., Auerbach,  S., Blackshear,  P. E., Bradley,  A., Gruebbel,  M. M., Little, P. B., Malarkey,  D., Maronpot,  R., McKay,  J. S., Miller, R. A., Moore, R. R., Morrison,  J. P., Nyska, A., Ramot, Y., Rao, D., Suttie, A., Wells, M. Y., Willson,  G. A., and Elmore,  S. A. (2011). Proceedings of the 2010 National Toxicology Program Satellite Symposium.  Toxicol Pathol 39, 240-266.  

Maronpot,  R. R. (2011). Responsible authorship and publication practices.  Toxicol Pathol 39, 1029-1031. Hobbs, C. A., Swartz,  C., Maronpot,  R., Davis, J., Recio, L., and Hayashi,  S. M. (2012). Evaluation of the genotoxicity of the food additive, gum ghatti. Food Chem Toxicol 50, 854-860.    

Hall, A.P., Elcombe,  C.R., Foster, J.R., Harada,  T., Kaufmann,  W., Knippel,  A., Kuttler, K., Malarkey,  D.E., Maronpot,  R.R., Nishikawa,  A., Nolte, T., Schulte,  A., Strauss,  V. & York, M.J. (2012). Liver Hypertrophy:A Review  of Adaptive  (Adverse  and Non-adverse)  Changes--Conclusions  from the 3rd International  ESTP Expert Workshop.  Toxicol Pathol, 40, 971-994.    

Carter, C.A., Misra, M. & Maronpot,  R.R. (2012). Tracheal Morphologic and Protein Alterations Following Short-Term Cigarette  Mainstream Smoke Exposure to Rats. J Toxicol Pathol, 25, 201-207.  

Thoolen, B., Ten Kate, F.J., van Diest, P.J., Malarkey,  D.E., Elmore,  S.A. & Maronpot,  R.R. (2012). Comparative  histomorphological  review of rat and human hepatocellular  proliferative  lesions.  J Toxicol Pathol, 25, 189-199.  

Maronpot, R.R. (2012). Regulatory forum opinion  piece: the role of the toxicologic  pathologist in the postgenomic  era:challenges and opportunities.  Toxicol Pathol, 40, 1082-1086.  

Maronpot, R.R., Davis, J., Moser, G., Giri, D.K. & Hayashi, S.M. (2013). Evaluation of 90-day oral rat toxicity studies on the food additive, gum ghatti. Food Chem Toxicol. 51:215-24.  

Branca, R. T., Zhang, L., Warren, W. S., Auerbach, E., Khanna, A., Degan, S., Ugurbil, K., and Maronpot, R. (2013). In vivo noninvasive detection of brown adipose tissue through intermolecular zero-quantum MRI. PLoS One 8, e74206.  

Elmore, S. A., Hoenerhoff, M., Katsuta, O., Kokoshima, H., Maronpot, R., Nagai, H., Satoh, H., Tanaka, Y., Tochitani, T., Tsuchiya, S., and Yoshizawa, K. (2013). Proceedings of the 2013 Joint JSTP/NTP Satellite Symposium. J Toxicol Pathol 26, 231-257.  

Maronpot, R. R. (2013). The role of the toxicologic pathologist in the post-genomic era. J Toxicol Pathol 26, 105-110.  

Maronpot, R. R., Thoolen, R. J., and Hansen, B. (2015). Two-year carcinogenicity study of acrylamide in Wistar Han rats with in utero exposure. Exp Toxicol Pathol 67, 189-95.  

Maronpot, R. R. (2015). Toxicological assessment of Ashitaba Chalcone. Food and Chemical Toxicology. 77: 111-119.

Book Chapters/Fascicles

Maronpot  RR, 1985. Considerations  in the Evaluation  and Interpretation  of Long-Term  Animal Bioassays  for Carcinogenicity.   In: Handbook  of Carcinogen  Testing.  Noyes Pub, NJ, pp. 372-382.  

Mennear  J, Maronpot  R, Boorman  G, Eustis S, Huff J, Haseman  J, McConnell  E, Ragan H, and Miller R, 1986. Toxicologic  and Carcinogenic  Effects of Inhaled  Tetrachloroethylene  in Rats and Mice. In: New Concepts  and Developments  in Toxicology.  Chambers  P L, Gehring  P, and Sakai F, eds. pp. 201-210.  

Maronpot  RR, 1986. Spontaneous  Hydronephrosis  in the Rat. In: ILSI Monograph  on Pathology  of Laboratory  Animals  - Urinary  System.  Springer-Verlag,   NY, pp. 268-271.  

Anderson  MW, Maronpot  RR, and Reynolds  SH, 1988. Role of Oncogenes  in Chemical Carcinogenesis:   Extrapolation  from Rodents  to Humans.  In: Detection  Methods  for DNA-Damaging Agents in Men: Applications  in Cancer Epidemiology  and Prevention.  Bartsch  H, et al., eds. IARC Scientific  Publication  #89, Oxford Univ. Press, pp. 477-485.  

Mitsumori  K, Dittrich KL, Stefanski  S, and Maronpot  RR, 1988. Benign  and Malignant  Neoplasms, Meninges,  Rat. In: ILSI Monograph  on Pathology  of Laboratory  Animals  - Nervous  System. Springer-Verlag,   NY, pp. 108-117.  

Maronpot  RR, 1990. Tumors  of the Liver. In: Atlas of Tumor Pathology  of the Fischer  Rat. CRC Press, pp. 193-220.  

Belinsky  SA, Walker VE, Uraih LC, Maronpot  RR, Swenberg  JA, and Anderson  MW, 1990. Role of DNA Adduct Formation  and Cell Proliferation  in the Induction  of Nasal Tumors  in the Rat by the Tobacco  Specific  Carcinogen  4-(N-methyl-N-nitrosamino)-1-  (3-pyridyl)-1-butanone.  In: Nasal Carcinogenesis  in Rodents:  Relevance  to Human  Health Risk. Pudoc Wageningen,  Netherlands, pp. 146-151.

You M, Reynolds  SH, Maronpot  RR, Stoner GD, and Anderson  MW 1990. Activated  Oncogenes  in Rodent and Human  Lung Tumors.  In: Biology,  Toxicology,  and Carcinogenesis  of Respiratory Epithelium.  Thomassen  DG and Nettesheim  P, eds. Hemisphere  Publishing  Co., NY, pp. 271-287.    

Maronpot  RR, 1991. Chemical  Carcinogenesis.   In: Handbook  of Toxicologic  Pathology.  Haschek  W and Rosseaux  CG, eds. Academic  Press, NY, pp. 99-129.  

Swenberg  JA and Maronpot  RR, 1991. Chemically  Induced  Cell Proliferation  as a Criterion  in Selecting  Doses for Long-term  Bioassays.  In: Chemically  Induced  Cell Proliferation:  Implications  for Risk Assessment  . Butterworth  BE, Slaga TJ, Farland  W, and McClain  M, eds. Vol. 369 of Progress in Clinical and Biological  Research.  Willy-Liss,  Inc., NY, pp. 245-251.  

Ghanayem  BI, Maronpot  RR, and Matthews  HB, 1991. Role of Chemically  Induced  Cell Proliferation in Ethyl Acrylate-induced   Forestomach  Carcinogenesis.  In: Chemically  Induced  Cell Proliferation:  Implications  for Risk Assessment.  Butterworth  BE, Slaga TJ, Farland  W, and McClain M, eds. Vol. 369 of Progress  in Clinical and Biological  Research.  Willy-Liss,  Inc., NY, pp. 337-346.  

Frantz JD, Betton G, Cartwright  ME, Crissman  JW, Macklin  AW, and Maronpot  RR, 1991. Proliferative  Lesions  of the Non-glandular  and Glandular  Stomach  in Rats. In: Guides for Toxicologic  Pathology.  STP/ARP/AFIP,  Washington,  DC, pp. 1-20.  

Clark G, Tritscher  A, Maronpot  R, Foley J, and Lucier G, 1991. Tumor Promotion  by TCDD in Female  Rats. In: Banbury  Report 35 - Biological  Basis for Risk Assessment  of dioxins and Related Compounds.  Cold Spring Harbor Laboratory  Press, Cold Spring Harbor,  pp. 389-404.  

Anderson  M, Stanley  L, Devereux  T, Reynolds  S, and Maronpot  R, 1992. Oncogenes  in Mouse Liver Tumors.  In: Comparative  Molecular  Carcinogenesis.   Klein-Szanto  AJP, Anderson  MS, Barrett JC, and Slaga TJ, eds. Wiley-Liss,  Inc., NY, pp. 187-201.  

Johnson GA, Benveniste  H, Black RR, Cofer GP, Gewalt SL, Hedlund LW, Maronpot RR, and Suddarth SA, 1992. MR Microscopy  of Disease Models. In: Magnetic Resonance  Microscopy: Methods  and Applications  in Materials  Science  and Biomedicine.  Blumich  B and Kuhn W, eds. VHC, NY, pp. 501-511.  

Dixon D and Maronpot  RR, 1994. Tumours  of the Pancreas.  In: Pathology  of Tumours  in Laboratory  Animals,  Vol. 2. Tumours  of the Mouse.  IARC Publications,  Lyon, pp. 281-303.  

Goodman  DG, Maronpot  RR, Newberne  PN, Popp JA, and Squire RA, 1994. Proliferative  and Selected  Other Lesions  in the Liver of Rats. In: Guides for Toxicologic  Pathology.  STP/ARP/AFIP, Washington,  DC, pp. 1-24.  

Maronpot  RR, Anna CH, Devereux  TR, Lucier GW, Butterworth  BE, and Anderson  MW, 1995. Considerations  Concerning  the Murine Hepatocarcinogenicity  of Selected  Chlorinated Hydrocarbons.  In: Implications  for Risk Assessment.  Wiley-Liss,  Inc., NY, pp. 305-323.  

Davis BJ and Maronpot  RR, 1996. Chemically  Associated  Toxicity  and Carcinogenicity  of the Ovary. In: Cellular  and Molecular  Mechanisms  of Hormonal  Carcinogenesis.  Environmental Influences.  Huff J, Boyd J, and Barrett JC, eds. Wiley-Liss,  NY, pp. 285-308.  

Kanno J, Ward JM, and Maronpot  RR, 1996. Mechanisms  of Chemically  Induced  Thyroid  Follicular Carcinogenesis.   In: Cellular  and Molecular  Mechanisms  of Hormonal  Carcinogenesis. Environmental  Influences.  Huff J, Boyd J, and Barrett JC, eds. Wiley-Liss,  NY, pp. 353-398.  

Devereux  TR, Malarkey  DE and Maronpot,  RR.  1996. The contribution  of rodent liver and lung carcinogenesis  models to our knowledge  of the cancer latent period.   In Maltoni,  C. (ed) , The Scientific  Bases of Cancer Chemoprevention.    Elsevier  Publications,  Amsterdam,  Netherlands.  pp. 45-59.

Harada,  T, Maronpot,  RR, Enomoto,  A, Tamano,  S and Ward, JM.  1996.  Changes  in the liver and gallbladder.   In: Pathobiology  of the Aging Mouse.   Volume  2.  Mohr, U, Dungworth,  DL, Capen, CC, Carlton,  WW, Sundberg,  JP and Ward, JM (Eds).  ILSI Press, Washington,  DC.  pp: 207-241.

Maronpot,  RR. 1998. Chemical  Carcinogenesis.    In: Fundamentals  of Toxicologic  Pathology. Haschek,  WM and Rousseaux,  CG (Eds).  Academic  Press, New York. pp. 15-35        

Maronpot,  RR. 1998. Carcinogenesis.    In: Encyclopedia  of Toxicology.   Wexler,  P. (Ed.). Academic Press, Ney York.  pp. 246-268.  

Nyska A and Maronpot  RR. 1999.  Adrenal  gland.  In: Pathology  of the Mouse.   Maronpot  RR, Boorman  GA and Gaul BW (Eds.).   Cache River Press, Vienna,  IL.  pp. 509-536.  

Harada  T, Enomoto  A, Boorman  GA and Maronpot  RR. 1999. Liver and gallbladder.  .  In: Pathology of the Mouse.   Maronpot  RR, Boorman  GA and Gaul BW (Eds.).   Cache River Press, Vienna,  IL. pp. 119-184.  

Mastroides  S and Maronpot  RR (2002) Carcinogenesis.    In: Handbook  of Toxicologic  Pathology.  2nd Edition.Haschek   WM, Russeaue  CG and Wallig MA (Eds). Academic  Press, San Diego. pp. 83- 122.  

Malarkey  DE and Maronpot  RR (2005) Carcinogenesis.   In: Encyclopedia  of Toxicology.  2nd Edition. Wexler,  P (Ed). Elsevier,  New York.  pp. 445-466.  
Maronpot,  R. R. (2007) Cancer Bioassays.  In: The Cancer Handbook,  Second  Edition.  Alison, MR (Ed). John Wiley and Sons Ltd., West Sussex,  England.

Co-Edited Symposia Proceedings  

Alison R and Maronpot  RR, 1987. Comparative  Ovarian  Pathology.  EHP 73:3-130.  

Maronpot  RR and Stitzel KA, 1989. Significance  of Foci of Cellular  Alteration  in the Rat Liver. Tox. Path. 17, No. 4 (Part 1), 557-735.  

Uraih LC, Morgan  KT, and Maronpot  RR, 1990. Symposium  on Toxicologic  Pathology  of the Upper Respiratory  System.  EHP 85:161-352.

Edited Books  

Maronpot  RR, Boorman  GA and Gaul BW.  1999.  Pathology  of the Mouse.   Cache River Press, Vienna,  Va.  699 pages.  

Pathology  of Genetically  Engineered  Mice.  2000.  Ward, JM, Mahler,  JF, Maronpot,  RR,Sundberg, JP (Eds).  Iowa State University  Press, Ames, Iowa.  pp. 394.

Edited  Monographs  

Guest Editor for A Monograph  on Histomorphologic  Evaluation  of Lymphoid Organs (2006). Toxicol Pathol 34 (5): 407-696.  

Production of Educational CDs

Lesions of Genetically  Altered Mice. Version 2. June 2001.

A Digitized Atlas of Mouse Liver Lesions. Version 1. April 2002.

A Digitized Atlas of Mouse Liver Lesions. Version 2. June 2002.

An Exercise in Peer Review: The Pathology Working Group.  An STP Satellite Symposium.  June 14, 2003.

A Digitized Atlas of Rat Liver Lesions. Version 1. June 2004.

A Digitized Atlas of Mouse Liver Lesions. Version 3. June 2004.